Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00040869" target="_blank" >RIV/00216224:14110/10:00040869 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
čeština
Název v původním jazyce
Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
Popis výsledku v původním jazyce
PURPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS: The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients(32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16).
Název v anglickém jazyce
Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology
Popis výsledku anglicky
URPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS:The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients(32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16).
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
FF - ORL, oftalmologie, stomatologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NR8507" target="_blank" >NR8507: DNA diagnostika bakteriálních a virových zánětů rohovky</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů