Family history and lung cancer risk: international multicentre case-control study in Eastern and Central Europe and meta-analyses Cancer Causes and Control.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00051820" target="_blank" >RIV/00216224:14110/10:00051820 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s10552-010-9537-2" target="_blank" >http://dx.doi.org/10.1007/s10552-010-9537-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10552-010-9537-2" target="_blank" >10.1007/s10552-010-9537-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Family history and lung cancer risk: international multicentre case-control study in Eastern and Central Europe and meta-analyses Cancer Causes and Control.

Popis výsledku v původním jazyce

Lung cancer is the most common neoplastic disease in Eastern and Central Europe. The role of hereditary factors in lung carcinogenesis is not fully understood. Family history (FH) of lung cancer and other tobacco-related cancers might be a strong predictor of the lung cancer risk. We investigated family history of cancer among first-degree relatives of 2,861 patients with lung cancer and 3,118 controls from the Czech Republic, Hungary, Poland, Romania, Russia, Slovakia, and United Kingdom within the IARC Multicenter Case-Control Study. Odds ratios (ORs) and 95% CI were calculated using logistic regression, adjusting for age, gender, study center, education, tobacco smoking, and number of first-degree relatives. In addition, we conducted a meta-analysisof 41 studies on FH of cancer and lung cancer risk. Positive FH of lung cancer increased risk of lung cancer with OR of 1.63 (95%CI: 1.31-2.

Název v anglickém jazyce

Family history and lung cancer risk: international multicentre case-control study in Eastern and Central Europe and meta-analyses Cancer Causes and Control.

Popis výsledku anglicky

Lung cancer is the most common neoplastic disease in Eastern and Central Europe. The role of hereditary factors in lung carcinogenesis is not fully understood. Family history (FH) of lung cancer and other tobacco-related cancers might be a strong predictor of the lung cancer risk. We investigated family history of cancer among first-degree relatives of 2,861 patients with lung cancer and 3,118 controls from the Czech Republic, Hungary, Poland, Romania, Russia, Slovakia, and United Kingdom within the IARC Multicenter Case-Control Study. Odds ratios (ORs) and 95% CI were calculated using logistic regression, adjusting for age, gender, study center, education, tobacco smoking, and number of first-degree relatives. In addition, we conducted a meta-analysisof 41 studies on FH of cancer and lung cancer risk. Positive FH of lung cancer increased risk of lung cancer with OR of 1.63 (95%CI: 1.31-2.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cancer causes and control

ISSN

0957-5243

e-ISSN

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Svazek periodika

21

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

14

Strana od-do

1091-1104

Kód UT WoS článku

000278615900012

EID výsledku v databázi Scopus

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