Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00054875" target="_blank" >RIV/00216224:14110/11:00054875 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s10856-011-4329-0" target="_blank" >http://dx.doi.org/10.1007/s10856-011-4329-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10856-011-4329-0" target="_blank" >10.1007/s10856-011-4329-0</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
Popis výsledku v původním jazyce
A sputtering technique followed by a low temperature hydrothermal treatment has been demonstrated to produce a dense-and-bioactive hydroxyapatite thin film coating. The purpose of the present study was to investigate osteoblast and osteoclast responses to the hydroxyapatite coated plates and titanium plates with similar roughness. Rat bone marrow stromal cells were cultured on these plates to induce osteoblasts. The cells showed a significantly enhanced proliferation on the hydroxyapatite surface, accompanied by increase of osteoblastic phenotypes. The co-cultured osteoclasts exhibited the significantly different cell number and morphology between the hydroxyapatite and the titanium surfaces. A series of osteoclast marker genes were more stimulated onthe hydroxyapatite and thirty two percent of the hydroxyapatite surface area could be resorbed by osteoclasts.
Název v anglickém jazyce
Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
Popis výsledku anglicky
A sputtering technique followed by a low temperature hydrothermal treatment has been demonstrated to produce a dense-and-bioactive hydroxyapatite thin film coating. The purpose of the present study was to investigate osteoblast and osteoclast responses to the hydroxyapatite coated plates and titanium plates with similar roughness. Rat bone marrow stromal cells were cultured on these plates to induce osteoblasts. The cells showed a significantly enhanced proliferation on the hydroxyapatite surface, accompanied by increase of osteoblastic phenotypes. The co-cultured osteoclasts exhibited the significantly different cell number and morphology between the hydroxyapatite and the titanium surfaces. A series of osteoclast marker genes were more stimulated onthe hydroxyapatite and thirty two percent of the hydroxyapatite surface area could be resorbed by osteoclasts.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FF - ORL, oftalmologie, stomatologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/1M0528" target="_blank" >1M0528: Stomatologické výzkumné centrum</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2011
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
ISSN
0957-4530
e-ISSN
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Svazek periodika
22
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
JP - Japonsko
Počet stran výsledku
11
Strana od-do
1489-1499
Kód UT WoS článku
000291702500013
EID výsledku v databázi Scopus
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