Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00080228" target="_blank" >RIV/00216224:14110/11:00080228 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/mds.23444" target="_blank" >http://dx.doi.org/10.1002/mds.23444</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mds.23444" target="_blank" >10.1002/mds.23444</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease

Popis výsledku v původním jazyce

We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that ?regardless of the presence of dopaminergic denervation, cerebrovascular lesions ? have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism?. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.

Název v anglickém jazyce

Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease

Popis výsledku anglicky

We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that ?regardless of the presence of dopaminergic denervation, cerebrovascular lesions ? have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism?. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Movement Disorders

ISSN

0885-3185

e-ISSN

—

Svazek periodika

26

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

1363

Kód UT WoS článku

000291863600036

EID výsledku v databázi Scopus

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