Kinetics of bilirubin and liver enzymes is useful for predicting of liver graft-versus-host disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060967" target="_blank" >RIV/00216224:14110/12:00060967 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/12:#0001842

Výsledek na webu

<a href="http://dx.doi.org/10.4149/neo_2012_034" target="_blank" >http://dx.doi.org/10.4149/neo_2012_034</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/neo_2012_034" target="_blank" >10.4149/neo_2012_034</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Kinetics of bilirubin and liver enzymes is useful for predicting of liver graft-versus-host disease

Popis výsledku v původním jazyce

Graft-versus-host disease (GVHD) is the most frequent complication after allogeneic hematopoietic cell transplantation. We analyzed the kinetics of bilirubin and liver enzymes in 47 cases with liver GVHD and in 47 cases without GVHD after allogeneic transplantation for various hematological malignancies. The duration of an liver GVHD episode (LGVHD) was defined as the interval from the point when the criteria of LGVHD were met to the decrease to &lt; 2 upper normal limit (UNL) for aminotransferases or bilirubin &lt; 34 mu mol/l for bilirubin. The imminent LGVHD episode was defined as the interval from the start of continuous increase (&gt;= 3 consecutive rising values) of bilirubin and liver enzymes above UNL to the point of LGVHD diagnosis. The numberof imminent LGVHD episodes, and median length in days were as follows: bilirubin (39;5), ALT(28;12), AST(9;12), GGTP(34;9), and ALP(13;14).

Název v anglickém jazyce

Kinetics of bilirubin and liver enzymes is useful for predicting of liver graft-versus-host disease

Popis výsledku anglicky

Graft-versus-host disease (GVHD) is the most frequent complication after allogeneic hematopoietic cell transplantation. We analyzed the kinetics of bilirubin and liver enzymes in 47 cases with liver GVHD and in 47 cases without GVHD after allogeneic transplantation for various hematological malignancies. The duration of an liver GVHD episode (LGVHD) was defined as the interval from the point when the criteria of LGVHD were met to the decrease to &lt; 2 upper normal limit (UNL) for aminotransferases or bilirubin &lt; 34 mu mol/l for bilirubin. The imminent LGVHD episode was defined as the interval from the start of continuous increase (&gt;= 3 consecutive rising values) of bilirubin and liver enzymes above UNL to the point of LGVHD diagnosis. The numberof imminent LGVHD episodes, and median length in days were as follows: bilirubin (39;5), ALT(28;12), AST(9;12), GGTP(34;9), and ALP(13;14).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neoplasma

ISSN

0028-2685

e-ISSN

—

Svazek periodika

59

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

5

Strana od-do

264-268

Kód UT WoS článku

000301966700004

EID výsledku v databázi Scopus

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