Možnosti modulace průběhu kardiovaskulárních chorob

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00062652" target="_blank" >RIV/00216224:14110/12:00062652 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

čeština

Název v původním jazyce

Možnosti modulace průběhu kardiovaskulárních chorob

Popis výsledku v původním jazyce

Lot of attention is paid to vitamin D in last few years due to brighter spectrum of influence in human organs. As a main mechanism of action are proved nuclear vitamin D receptors (VDR). More and more evidence of negative influence of vitamin D deficit on cardiovascular system appears together with low vitamin D serum levels in current population mostly due to life style with little exposition of unprotected skin to sun beams. The course of ischemic heart disease can be worsened by low serum level of vitamin D because of higher risk of myocardial infarction a cardiac failure with more frequent hospitalisations. Higher risk of arrythmias during vitamin D deficiency is explained by higher production of parathormone and its binding to receptors stimulating phospholipase C followed by increased activity of catecholamines, angiotensin II and endothelin in ischaemic myocardium.

Název v anglickém jazyce

Possible modulation of the course of cardiovascular diseases

Popis výsledku anglicky

Lot of attention is paid to vitamin D in last few years due to brighter spectrum of influence in human organs. As a main mechanism of action are proved nuclear vitamin D receptors (VDR). More and more evidence of negative influence of vitamin D deficit on cardiovascular system appears together with low vitamin D serum levels in current population mostly due to life style with little exposition of unprotected skin to sun beams. The course of ischemic heart disease can be worsened by low serum level of vitamin D because of higher risk of myocardial infarction a cardiac failure with more frequent hospitalisations. Higher risk of arrythmias during vitamin D deficiency is explained by higher production of parathormone and its binding to receptors stimulating phospholipase C followed by increased activity of catecholamines, angiotensin II and endothelin in ischaemic myocardium.

Druh

O - Ostatní výsledky

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů