Could rising BUN predict the future development of infected pancreatic necrosis?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069861" target="_blank" >RIV/00216224:14110/13:00069861 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.pan.2013.05.003" target="_blank" >http://dx.doi.org/10.1016/j.pan.2013.05.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pan.2013.05.003" target="_blank" >10.1016/j.pan.2013.05.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Could rising BUN predict the future development of infected pancreatic necrosis?

Popis výsledku v původním jazyce

Background: Infected (peri)pancreatic necrosis (IPN) in acute pancreatitis (AP) is associated with organ failure (OF) and high mortality. There are no established early markers of primary IPN. This study aimed to assess the association of simple parameters with primary IPN in AP. Methods: We retrospectively studied 281 patients with AP admitted to Mayo Clinic hospitals and identified those with microbiologically confirmed infections in (peri)pancreatic necrosis and collections. We defined primary IPN asinfection of (peri)pancreatic necrotic tissue that developed before interventions. We recorded admission hematocrit, BMI, BUN, serum creatinine, SIRS score and development of persistent organ failure within 48 h of admission; and performed serial SIRS and BUN calculations for at least 48 h. We used univariate and multivariable analysis to assess associations and expressed results as odds ratio (OR)[95% CI]. Results: 27(9.6%) patients developed IPN, of which 21(77.7%) had primary IPN. 38

Název v anglickém jazyce

Could rising BUN predict the future development of infected pancreatic necrosis?

Popis výsledku anglicky

Background: Infected (peri)pancreatic necrosis (IPN) in acute pancreatitis (AP) is associated with organ failure (OF) and high mortality. There are no established early markers of primary IPN. This study aimed to assess the association of simple parameters with primary IPN in AP. Methods: We retrospectively studied 281 patients with AP admitted to Mayo Clinic hospitals and identified those with microbiologically confirmed infections in (peri)pancreatic necrosis and collections. We defined primary IPN asinfection of (peri)pancreatic necrotic tissue that developed before interventions. We recorded admission hematocrit, BMI, BUN, serum creatinine, SIRS score and development of persistent organ failure within 48 h of admission; and performed serial SIRS and BUN calculations for at least 48 h. We used univariate and multivariable analysis to assess associations and expressed results as odds ratio (OR)[95% CI]. Results: 27(9.6%) patients developed IPN, of which 21(77.7%) had primary IPN. 38

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pancreatology

ISSN

1424-3903

e-ISSN

—

Svazek periodika

13

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

5

Strana od-do

355-359

Kód UT WoS článku

000323464600006

EID výsledku v databázi Scopus

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