Status Update and Interim Results from the Asymptomatic Carotid Surgery Trial-2 (ACST-2)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00071242" target="_blank" >RIV/00216224:14110/13:00071242 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00843989:_____/13:E0103753 RIV/00159816:_____/13:00060679 RIV/61989592:15120/13:33149365

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ejvs.2013.07.020" target="_blank" >http://dx.doi.org/10.1016/j.ejvs.2013.07.020</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejvs.2013.07.020" target="_blank" >10.1016/j.ejvs.2013.07.020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Status Update and Interim Results from the Asymptomatic Carotid Surgery Trial-2 (ACST-2)

Popis výsledku v původním jazyce

Objectives: ACST-2 is currently the largest trial ever conducted to compare carotid artery stenting (CAS) with carotid endarterectomy (CEA) in patients with severe asymptomatic carotid stenosis requiring revascularization. Methods: Patients are entered into ACST-2 when revascularization is felt to be clearly indicated, when CEA and CAS are both possible, but where there is substantial uncertainty as to which is most appropriate. Trial surgeons and interventionalists are expected to use their usual techniques and CE-approved devices. We report baseline characteristics and blinded combined interim results for 30-day mortality and major morbidity for 986 patients in the ongoing trial up to September 2012. Results: A total of 986 patients (687 men, 299 women), mean age 68.7 years (SD +/- 8.1) were randomized equally to CEA or CAS. Most (96%) had ipsilateral stenosis of 70-99% (median 80%) with contralateral stenoses of 50-99% in 30% and contralateral occlusion in 8%.

Název v anglickém jazyce

Status Update and Interim Results from the Asymptomatic Carotid Surgery Trial-2 (ACST-2)

Popis výsledku anglicky

Objectives: ACST-2 is currently the largest trial ever conducted to compare carotid artery stenting (CAS) with carotid endarterectomy (CEA) in patients with severe asymptomatic carotid stenosis requiring revascularization. Methods: Patients are entered into ACST-2 when revascularization is felt to be clearly indicated, when CEA and CAS are both possible, but where there is substantial uncertainty as to which is most appropriate. Trial surgeons and interventionalists are expected to use their usual techniques and CE-approved devices. We report baseline characteristics and blinded combined interim results for 30-day mortality and major morbidity for 986 patients in the ongoing trial up to September 2012. Results: A total of 986 patients (687 men, 299 women), mean age 68.7 years (SD +/- 8.1) were randomized equally to CEA or CAS. Most (96%) had ipsilateral stenosis of 70-99% (median 80%) with contralateral stenoses of 50-99% in 30% and contralateral occlusion in 8%.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

ISSN

1078-5884

e-ISSN

—

Svazek periodika

46

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

510-518

Kód UT WoS článku

000327232500004

EID výsledku v databázi Scopus

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