The fetal inflammatory response in subgroups of women with preterm prelabor rupture of the membranes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00071392" target="_blank" >RIV/00216224:14110/13:00071392 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/13:10139094 RIV/65269705:_____/13:#0002110 RIV/00179906:_____/13:10139094

Výsledek na webu

<a href="http://dx.doi.org/10.3109/14767058.2013.765404" target="_blank" >http://dx.doi.org/10.3109/14767058.2013.765404</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/14767058.2013.765404" target="_blank" >10.3109/14767058.2013.765404</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The fetal inflammatory response in subgroups of women with preterm prelabor rupture of the membranes

Popis výsledku v původním jazyce

Objective: To evaluate the influence of microbial invasion of the amniotic cavity (MIAC) and histological chorioamnionitis (HCA) on the intensity of the fetal inflammatory response and the occurrence of fetal inflammatory response syndrome (FIRS) in preterm prelabor rupture of membranes (PPROM). Methods: One hundred and forty-nine women with singleton pregnancies complicated by PPROM between the gestational ages 24+0 and 36+6 weeks were included in the study. Blood samples were obtained by venipuncturefrom the umbilical cord after the delivery of the newborn. The umbilical cord blood interleukin (IL)-6 levels were evaluated using ELISA kits. The fetal inflammatory response was determined by IL-6 levels, and FIRS was defined as an umbilical cord bloodIL-6 &gt;11 pg/mL. Result: IL-6 levels and the occurrence of FIRS were higher in women complicated with both MIAC and HCA (median IL-6 35.5 pg/mL, FIRS in 68%) than in women with HCA alone (median IL-6 5.8 pg/mL, FIRS in 36%), MIAC alone

Název v anglickém jazyce

The fetal inflammatory response in subgroups of women with preterm prelabor rupture of the membranes

Popis výsledku anglicky

Objective: To evaluate the influence of microbial invasion of the amniotic cavity (MIAC) and histological chorioamnionitis (HCA) on the intensity of the fetal inflammatory response and the occurrence of fetal inflammatory response syndrome (FIRS) in preterm prelabor rupture of membranes (PPROM). Methods: One hundred and forty-nine women with singleton pregnancies complicated by PPROM between the gestational ages 24+0 and 36+6 weeks were included in the study. Blood samples were obtained by venipuncturefrom the umbilical cord after the delivery of the newborn. The umbilical cord blood interleukin (IL)-6 levels were evaluated using ELISA kits. The fetal inflammatory response was determined by IL-6 levels, and FIRS was defined as an umbilical cord bloodIL-6 &gt;11 pg/mL. Result: IL-6 levels and the occurrence of FIRS were higher in women complicated with both MIAC and HCA (median IL-6 35.5 pg/mL, FIRS in 68%) than in women with HCA alone (median IL-6 5.8 pg/mL, FIRS in 36%), MIAC alone

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

<a href="/cs/project/NT13461" target="_blank" >NT13461: Vztah mezi množstvím bakterií v plodové vodě a intenzitou intraamniální zánětlivé odpovědi u pacientek s předčasným odtokem plodové vody</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF MATERNAL-FETAL &amp; NEONATAL MEDICINE

ISSN

1476-7058

e-ISSN

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Svazek periodika

26

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

795-801

Kód UT WoS článku

000317929600012

EID výsledku v databázi Scopus

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