Body Mass Index and Mortality in Acutely Decompensated Heart Failure Across the World

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00074969" target="_blank" >RIV/00216224:14110/14:00074969 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/14:00061601

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jacc.2013.09.072" target="_blank" >http://dx.doi.org/10.1016/j.jacc.2013.09.072</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jacc.2013.09.072" target="_blank" >10.1016/j.jacc.2013.09.072</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Body Mass Index and Mortality in Acutely Decompensated Heart Failure Across the World

Popis výsledku v původním jazyce

Objective To define the relationship between body mass index (BMI) and mortality in heart failure (HF) across the world and identify specific groups in whom BMI may differentially mediate risk. Background Obesity is associated with incident heart failure(HF), but is paradoxically associated with better prognosis during chronic HF. Methods We studied 6,142 patients with acute decompensated HF from 12 prospective observational cohorts followed across 4 continents. Primary outcome was all-cause mortality.Cox proportional hazards models and net reclassification index (NRI) described associations of BMI with all-cause mortality. Results ?Normal? weight patients (BMI 18.5-25 kg/m2) were older with more advanced HF and lower cardiometabolic risk. Despite worldwide heterogeneity in clinical features across obesity categories, a higher BMI remained associated with decreased 30-day and 1-year mortality (11% decrease at 30 days; 9% decrease at 1 year per 5 kg/m2; P&lt;0.05), after adjustment fo

Název v anglickém jazyce

Body Mass Index and Mortality in Acutely Decompensated Heart Failure Across the World

Popis výsledku anglicky

Objective To define the relationship between body mass index (BMI) and mortality in heart failure (HF) across the world and identify specific groups in whom BMI may differentially mediate risk. Background Obesity is associated with incident heart failure(HF), but is paradoxically associated with better prognosis during chronic HF. Methods We studied 6,142 patients with acute decompensated HF from 12 prospective observational cohorts followed across 4 continents. Primary outcome was all-cause mortality.Cox proportional hazards models and net reclassification index (NRI) described associations of BMI with all-cause mortality. Results ?Normal? weight patients (BMI 18.5-25 kg/m2) were older with more advanced HF and lower cardiometabolic risk. Despite worldwide heterogeneity in clinical features across obesity categories, a higher BMI remained associated with decreased 30-day and 1-year mortality (11% decrease at 30 days; 9% decrease at 1 year per 5 kg/m2; P&lt;0.05), after adjustment fo

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of The American College of Cardiology

ISSN

0735-1097

e-ISSN

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Svazek periodika

63

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

778-785

Kód UT WoS článku

000331720900005

EID výsledku v databázi Scopus

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