The magnitude and course of exercise-induced stroke volume changes determine the exercise tolerance in heart transplant recipients with heart failure and normal ejection fraction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075482" target="_blank" >RIV/00216224:14110/14:00075482 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/14:00061033 RIV/68081731:_____/14:00431978 RIV/00209775:_____/14:#0000305

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

The magnitude and course of exercise-induced stroke volume changes determine the exercise tolerance in heart transplant recipients with heart failure and normal ejection fraction

Popis výsledku v původním jazyce

Objectives: There is a large variability of exercise-induced stroke volume behavior in healthy subjects. We sought to assess the course of exercise-induced changes in stroke volume index (SVI) and other functional parameters in post-heart transplant patients with heart failure and normal left ventricular ejection fraction (HFNEF). Methods: Left ventricular function and systemic hemodynamics were assessed at 40 s intervals during the exercise in 39 patients using simultaneous right heart catheterization,bioimpedance, and echocardiography. Results: Twenty-six patients had exercise tolerance &gt;/= 4.0 METs (Group A), while 13 patients exhibited severely limited exercise tolerance &lt; 4 METs (Group B). Maximal SVI (maxSVI) achieved at any time during the exercise exceeded SVI at peak exercise (peakSVI) in 26 patients (67%). Both maxSVI and maxSVI (maxSVI minus SVI at rest) were significantly higher in Group A compared to Group B patients (59 ml/m2 vs 41 ml/m 2, p &lt; 0.

Název v anglickém jazyce

The magnitude and course of exercise-induced stroke volume changes determine the exercise tolerance in heart transplant recipients with heart failure and normal ejection fraction

Popis výsledku anglicky

Objectives: There is a large variability of exercise-induced stroke volume behavior in healthy subjects. We sought to assess the course of exercise-induced changes in stroke volume index (SVI) and other functional parameters in post-heart transplant patients with heart failure and normal left ventricular ejection fraction (HFNEF). Methods: Left ventricular function and systemic hemodynamics were assessed at 40 s intervals during the exercise in 39 patients using simultaneous right heart catheterization,bioimpedance, and echocardiography. Results: Twenty-six patients had exercise tolerance &gt;/= 4.0 METs (Group A), while 13 patients exhibited severely limited exercise tolerance &lt; 4 METs (Group B). Maximal SVI (maxSVI) achieved at any time during the exercise exceeded SVI at peak exercise (peakSVI) in 26 patients (67%). Both maxSVI and maxSVI (maxSVI minus SVI at rest) were significantly higher in Group A compared to Group B patients (59 ml/m2 vs 41 ml/m 2, p &lt; 0.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EXPERIMENTAL & CLINICAL CARDIOLOGY

ISSN

1205-6626

e-ISSN

—

Svazek periodika

20

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CA - Kanada

Počet stran výsledku

14

Strana od-do

674-687

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—