Determination of common urine substances as an assay for improving prostate carcinoma diagnostics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075838" target="_blank" >RIV/00216224:14110/14:00075838 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/14:00217540 RIV/00216208:11130/14:10292824 RIV/00216305:26620/14:PU108607 RIV/00159816:_____/14:00061362 RIV/00064203:_____/14:10292824

Výsledek na webu

<a href="http://dx.doi.org/10.3892/or.2014.3054" target="_blank" >http://dx.doi.org/10.3892/or.2014.3054</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3892/or.2014.3054" target="_blank" >10.3892/or.2014.3054</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determination of common urine substances as an assay for improving prostate carcinoma diagnostics

Popis výsledku v původním jazyce

Recently, interest in the identification of non-invasive markers for prostate carcinoma detectable in the urine of patients has increased. In this study, we monitored the abundance of potential non-invasive markers of prostate carcinoma such as amino acid sarcosine, involved in the metabolism of amino acids and methylation processes, ongoing during the progression of prostate carcinoma. In addition, other potential prostate tumor markers were studied. The most significant markers, prostate-specific antigen (PSA) and free PSA (fPSA), already used in clinical diagnosis, were analyzed using an immunoenzymometric assay. Whole amino acid profiles were also determined to evaluate the status of amino acids in patient urine samples and to elucidate the possibility of their utilization for prostate carcinoma diagnosis. To obtain the maximum amount of information, the biochemical parameters were determined using various spectrophotometric methods.

Název v anglickém jazyce

Determination of common urine substances as an assay for improving prostate carcinoma diagnostics

Popis výsledku anglicky

Recently, interest in the identification of non-invasive markers for prostate carcinoma detectable in the urine of patients has increased. In this study, we monitored the abundance of potential non-invasive markers of prostate carcinoma such as amino acid sarcosine, involved in the metabolism of amino acids and methylation processes, ongoing during the progression of prostate carcinoma. In addition, other potential prostate tumor markers were studied. The most significant markers, prostate-specific antigen (PSA) and free PSA (fPSA), already used in clinical diagnosis, were analyzed using an immunoenzymometric assay. Whole amino acid profiles were also determined to evaluate the status of amino acids in patient urine samples and to elucidate the possibility of their utilization for prostate carcinoma diagnosis. To obtain the maximum amount of information, the biochemical parameters were determined using various spectrophotometric methods.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Oncology Reports

ISSN

1021-335X

e-ISSN

—

Svazek periodika

31

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GR - Řecká republika

Počet stran výsledku

9

Strana od-do

1846-1854

Kód UT WoS článku

000334345600046

EID výsledku v databázi Scopus

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