Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077147" target="_blank" >RIV/00216224:14110/14:00077147 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/14:00061027

Výsledek na webu

<a href="http://dx.doi.org/10.1259/bjr.20130545" target="_blank" >http://dx.doi.org/10.1259/bjr.20130545</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1259/bjr.20130545" target="_blank" >10.1259/bjr.20130545</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

Popis výsledku v původním jazyce

Objective: Large artery occlusion (LAO) in patients with major stroke predicts poor revascularization by intravenous thrombolysis (IVT) and more likely results in a poor outcome. We focused on the effects of intra- arterial thrombolysis (IAT) and endovascular mechanical recanalization (EMR) as rescue therapies in major strokes refractory to IVT. Methods: A retrospective analysis of 87 patients (National Institutes of Health Stroke Scale &gt;20), who did not respond to full-dose IVT due to LAO, was performed based on their endovascular therapy status. IAT was performed as an intraclot infusion of alteplase, and EMR was provided by the Solitaire device (TM) (Covidien, Dubin, Ireland). The recanalization and 3-month outcome rates after IAT/EMR were correlated with a group of patients who were scheduled to receive endovascular treatment but who underwent only IVT. Results: We achieved successful recanalization by IAT and EMR in 68.7% and 76.1% of patients, respectively.

Název v anglickém jazyce

Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

Popis výsledku anglicky

Objective: Large artery occlusion (LAO) in patients with major stroke predicts poor revascularization by intravenous thrombolysis (IVT) and more likely results in a poor outcome. We focused on the effects of intra- arterial thrombolysis (IAT) and endovascular mechanical recanalization (EMR) as rescue therapies in major strokes refractory to IVT. Methods: A retrospective analysis of 87 patients (National Institutes of Health Stroke Scale &gt;20), who did not respond to full-dose IVT due to LAO, was performed based on their endovascular therapy status. IAT was performed as an intraclot infusion of alteplase, and EMR was provided by the Solitaire device (TM) (Covidien, Dubin, Ireland). The recanalization and 3-month outcome rates after IAT/EMR were correlated with a group of patients who were scheduled to receive endovascular treatment but who underwent only IVT. Results: We achieved successful recanalization by IAT and EMR in 68.7% and 76.1% of patients, respectively.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BRITISH JOURNAL OF RADIOLOGY

ISSN

0007-1285

e-ISSN

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Svazek periodika

87

Číslo periodika v rámci svazku

1036

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

"20130545"

Kód UT WoS článku

000334291900006

EID výsledku v databázi Scopus

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