Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077208" target="_blank" >RIV/00216224:14110/14:00077208 - isvavai.cz</a>
Výsledek na webu
—
DOI - Digital Object Identifier
—
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report
Popis výsledku v původním jazyce
We present a case report of one year old girl with recurrent laryngeal papillomatosis that was successfully treated by vaccination. The childs mother got condyloma acuminata during pregnancy. The disease was transmitted to the girl probably during delivery. At age of 5 months, the child started to present difficulties with breathing due to laryngeal papilomas. The disease required frequent papilectomies (almost every month) to maintain breathing. The papilomavirus type 11 was detected by PCR in the papiloma histology sample. At age of 18 months we started experimental vaccination with Gardasil* (it contains particles similar to HPV 6, 11, 16, 18). Intervals between necessary papilectomies were longer after the second dose of the vaccine. There was no need for further polypectomy after the third dose of the vaccine. At age of 30 months the child has no clinical and laryngoscope signs of laryngeal papillomatosis and the girl regained her voice.
Název v anglickém jazyce
Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report
Popis výsledku anglicky
We present a case report of one year old girl with recurrent laryngeal papillomatosis that was successfully treated by vaccination. The childs mother got condyloma acuminata during pregnancy. The disease was transmitted to the girl probably during delivery. At age of 5 months, the child started to present difficulties with breathing due to laryngeal papilomas. The disease required frequent papilectomies (almost every month) to maintain breathing. The papilomavirus type 11 was detected by PCR in the papiloma histology sample. At age of 18 months we started experimental vaccination with Gardasil* (it contains particles similar to HPV 6, 11, 16, 18). Intervals between necessary papilectomies were longer after the second dose of the vaccine. There was no need for further polypectomy after the third dose of the vaccine. At age of 30 months the child has no clinical and laryngoscope signs of laryngeal papillomatosis and the girl regained her voice.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
FN - Epidemiologie, infekční nemoci a klinická imunologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů