Hilar cholangiocarcinoma: palliation strategies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084677" target="_blank" >RIV/00216224:14110/15:00084677 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00270-015-1173-5" target="_blank" >http://dx.doi.org/10.1007/s00270-015-1173-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00270-015-1173-5" target="_blank" >10.1007/s00270-015-1173-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hilar cholangiocarcinoma: palliation strategies

Popis výsledku v původním jazyce

Tumours located in the hilar region often infiltrate early and encircle the vascular system (the branches of the common hepatic artery and portal vein), and cholangiocarcinomas also expand longitudinally into the intra- and extrahepatic bile ducts, submucosally and perineurially.The effect of systemic chemotherapy alone in the treatment of non-resectable cholangiocarcinomas is very limited. Stent implantation is an optimal solution for malignant obstructions in patients who are not candidates for surgical intervention and where the expected survival is longer than 3?6 months. IThe most frequent complication of SEMS is their closure. The stent gradually becomes covered with bile duct mucosa. In some patients, benign obstruction can occur due to its hyperplasia. Very frequently, stent occlusion is also associated with migration or closure by detritus and sludge formation. As disease progresses, there can occur ingrowth or overgrowth of the stent edge by the tumour.

Název v anglickém jazyce

Hilar cholangiocarcinoma: palliation strategies

Popis výsledku anglicky

Tumours located in the hilar region often infiltrate early and encircle the vascular system (the branches of the common hepatic artery and portal vein), and cholangiocarcinomas also expand longitudinally into the intra- and extrahepatic bile ducts, submucosally and perineurially.The effect of systemic chemotherapy alone in the treatment of non-resectable cholangiocarcinomas is very limited. Stent implantation is an optimal solution for malignant obstructions in patients who are not candidates for surgical intervention and where the expected survival is longer than 3?6 months. IThe most frequent complication of SEMS is their closure. The stent gradually becomes covered with bile duct mucosa. In some patients, benign obstruction can occur due to its hyperplasia. Very frequently, stent occlusion is also associated with migration or closure by detritus and sludge formation. As disease progresses, there can occur ingrowth or overgrowth of the stent edge by the tumour.

Druh

O - Ostatní výsledky

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů