Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084692" target="_blank" >RIV/00216224:14110/15:00084692 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/62156489:43210/15:43907790 RIV/00216305:26620/15:PU126733
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.bjid.2015.08.013" target="_blank" >http://dx.doi.org/10.1016/j.bjid.2015.08.013</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bjid.2015.08.013" target="_blank" >10.1016/j.bjid.2015.08.013</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration
Popis výsledku v původním jazyce
Background Infections, mostly those associated with colonization of wound by different pathogenic microorganisms, are one of the most serious health complications during a medical treatment. Therefore, this study is focused on the isolation, characterization, and identification of microorganisms prevalent in superficial wounds of patients (n = 50) presenting with bacterial infection. Methods After successful cultivation, bacteria were processed and analyzed. Initially the identification of the strains was performed through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry based on comparison of protein profiles (2?30 kDa) with database. Subsequently, bacterial strains from infected wounds were identified by both matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and sequencing of 16S rRNA gene 108. Results The most prevalent species was Staphylococcus aureus (70%), and out of those 11% turned out to be methicillin-resistant (mecA pos
Název v anglickém jazyce
Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration
Popis výsledku anglicky
Background Infections, mostly those associated with colonization of wound by different pathogenic microorganisms, are one of the most serious health complications during a medical treatment. Therefore, this study is focused on the isolation, characterization, and identification of microorganisms prevalent in superficial wounds of patients (n = 50) presenting with bacterial infection. Methods After successful cultivation, bacteria were processed and analyzed. Initially the identification of the strains was performed through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry based on comparison of protein profiles (2?30 kDa) with database. Subsequently, bacterial strains from infected wounds were identified by both matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and sequencing of 16S rRNA gene 108. Results The most prevalent species was Staphylococcus aureus (70%), and out of those 11% turned out to be methicillin-resistant (mecA pos
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FN - Epidemiologie, infekční nemoci a klinická imunologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Brazilian Journal of Infectious Diseases
ISSN
1413-8670
e-ISSN
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Svazek periodika
19
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
BR - Brazilská federativní republika
Počet stran výsledku
10
Strana od-do
604-613
Kód UT WoS článku
000365871300008
EID výsledku v databázi Scopus
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