Computer Analysis of Isolated Cardiomyocyte Contraction Process via Advanced Image Processing Techniques

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00087764" target="_blank" >RIV/00216224:14110/15:00087764 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/16:00065845

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Computer Analysis of Isolated Cardiomyocyte Contraction Process via Advanced Image Processing Techniques

Popis výsledku v původním jazyce

Isolated cardiomyocytes (CMs) have been used as valid and useful model in experimental cardiology research for decades. A single CMs is considered as a functional unit with electrical, signaling, and mechanical functions of cell excitation-contraction process. The contraction function is usually measured via expensive and complex instruments which can either damage the cell or take much time for setting up Atomic Force Microscopy (AMF). In contrary, recent development of optical microscopy and digital cameras suggests utilization of touch-less CMs video acquisition in connection with advanced image processing techniques for automatic and precise evaluation of CMs contraction process. A typical adult CMs is a cylindrically-shaped cell (approx. with length 100µm and diameter 25µm) that can be observed as a bright structure surrounded by dark curve in bright-field optical microscopy. The dark curve surrounding the CMs are formed by cell membrane that blocks and scatters visible light.

Název v anglickém jazyce

Computer Analysis of Isolated Cardiomyocyte Contraction Process via Advanced Image Processing Techniques

Popis výsledku anglicky

Isolated cardiomyocytes (CMs) have been used as valid and useful model in experimental cardiology research for decades. A single CMs is considered as a functional unit with electrical, signaling, and mechanical functions of cell excitation-contraction process. The contraction function is usually measured via expensive and complex instruments which can either damage the cell or take much time for setting up Atomic Force Microscopy (AMF). In contrary, recent development of optical microscopy and digital cameras suggests utilization of touch-less CMs video acquisition in connection with advanced image processing techniques for automatic and precise evaluation of CMs contraction process. A typical adult CMs is a cylindrically-shaped cell (approx. with length 100µm and diameter 25µm) that can be observed as a bright structure surrounded by dark curve in bright-field optical microscopy. The dark curve surrounding the CMs are formed by cell membrane that blocks and scatters visible light.

Druh

D - Stať ve sborníku

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Computing in Cardiology 2015

ISBN

9781509006854

ISSN

2325-887X

e-ISSN

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Počet stran výsledku

4

Strana od-do

453-456

Název nakladatele

IEEE Computer Society

Místo vydání

Washington

Místo konání akce

Nice

Datum konání akce

6. 9. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000380374700115