Malignant catatonia due to anti-NMDA-receptor encephalitis in a 15-year-old girl: case report and summary of current knowledge
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00091888" target="_blank" >RIV/00216224:14110/16:00091888 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Malignant catatonia due to anti-NMDA-receptor encephalitis in a 15-year-old girl: case report and summary of current knowledge
Popis výsledku v původním jazyce
Anti-N-methyl-D-aspartate receptor encephalitis is a recently identified autoimmune disorder with a prominent neuropsychiatric presentation. We present the case of a 15-yearold girl with partial complex seizures with secondary generalization and acute mania with psychotic features. A positive diagnosis of anti-NMDA-receptor encephalitis suggested the specific treatment. Despite first-line immune treatment, the patient progressed to stupor, malignant catatonia, and autonomic instability with the risk of cardiopulmonary function failure. She improved after second-line immunosuppressive therapy (cyclophosphamide and rituximab simultaneously). Post-cognitive sequelae (memory impairment and deliberation) disappeared within 8 months of follow-up treatment and intensive cognitive rehabilitation. This case report emphasizes the importance of differential diagnosis and adequate treatment of catatonic syndrome, especially in young adults.
Název v anglickém jazyce
Malignant catatonia due to anti-NMDA-receptor encephalitis in a 15-year-old girl: case report and summary of current knowledge
Popis výsledku anglicky
Anti-N-methyl-D-aspartate receptor encephalitis is a recently identified autoimmune disorder with a prominent neuropsychiatric presentation. We present the case of a 15-yearold girl with partial complex seizures with secondary generalization and acute mania with psychotic features. A positive diagnosis of anti-NMDA-receptor encephalitis suggested the specific treatment. Despite first-line immune treatment, the patient progressed to stupor, malignant catatonia, and autonomic instability with the risk of cardiopulmonary function failure. She improved after second-line immunosuppressive therapy (cyclophosphamide and rituximab simultaneously). Post-cognitive sequelae (memory impairment and deliberation) disappeared within 8 months of follow-up treatment and intensive cognitive rehabilitation. This case report emphasizes the importance of differential diagnosis and adequate treatment of catatonic syndrome, especially in young adults.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Neuropsychiatry
ISSN
1758-2008
e-ISSN
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Svazek periodika
6
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
136-141
Kód UT WoS článku
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EID výsledku v databázi Scopus
2-s2.0-85017703298