Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F18%3A00104186" target="_blank" >RIV/00216224:14110/18:00104186 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.crvasa.2017.11.006" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2017.11.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.crvasa.2017.11.006" target="_blank" >10.1016/j.crvasa.2017.11.006</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
Popis výsledku v původním jazyce
Aim: The aim of this study was to compare the setting of interventricular (VV) delay by 3D echocardiography (3DE) using systolic dyssynchrony index (SDI) versus QRS width measurement in new cardiac resynchronization therapy (CRT) recipients. We observed the impact on the reduction of left ventricle volumes and increase in volumetric responders (defined as a = 15% reduction in left ventricular end-systolic volume (LVESv)) at the 6-month follow-up. Methods: We included 63 patients with recently implanted CRT in this open-label, randomized trial. Patients were randomized into two groups. VV delay was set by the QRS width in the group 1 (n 31) to obtain the narrowest QRS complex and by SDI in the group 2 (n 32) to achieve the lowest possible value. We evaluated LVESv, left ventricular ejection fraction (LVEF) by 3DE, before CRT implantation and at 6-month follow-up, in all patients. We also obtained clinical parameters and the level of NT-proBNP. Results: The second group showed only a trend toward greater reduction of LVESv (-33 +/- 55 ml vs. -48 +/- 43 ml; P 0.367), increase in LVEF (+ 7.3 +/- 10.9% vs. + 10.2 +/- 9.4%; P 0.210) and greater number of volumetric responders (14 vs. 18; P 0.612) compared with the group 1 at 6-month follow-up. There were also no significant differences in clinical outcomes and the level of NT-proBNP. Conclusion: Individual CRT optimization using SDI compared with QRS duration assessment did not reveal any significant differences in echocardiographic parameters and clinical outcomes at 6-month follow-up. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.
Název v anglickém jazyce
Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
Popis výsledku anglicky
Aim: The aim of this study was to compare the setting of interventricular (VV) delay by 3D echocardiography (3DE) using systolic dyssynchrony index (SDI) versus QRS width measurement in new cardiac resynchronization therapy (CRT) recipients. We observed the impact on the reduction of left ventricle volumes and increase in volumetric responders (defined as a = 15% reduction in left ventricular end-systolic volume (LVESv)) at the 6-month follow-up. Methods: We included 63 patients with recently implanted CRT in this open-label, randomized trial. Patients were randomized into two groups. VV delay was set by the QRS width in the group 1 (n 31) to obtain the narrowest QRS complex and by SDI in the group 2 (n 32) to achieve the lowest possible value. We evaluated LVESv, left ventricular ejection fraction (LVEF) by 3DE, before CRT implantation and at 6-month follow-up, in all patients. We also obtained clinical parameters and the level of NT-proBNP. Results: The second group showed only a trend toward greater reduction of LVESv (-33 +/- 55 ml vs. -48 +/- 43 ml; P 0.367), increase in LVEF (+ 7.3 +/- 10.9% vs. + 10.2 +/- 9.4%; P 0.210) and greater number of volumetric responders (14 vs. 18; P 0.612) compared with the group 1 at 6-month follow-up. There were also no significant differences in clinical outcomes and the level of NT-proBNP. Conclusion: Individual CRT optimization using SDI compared with QRS duration assessment did not reveal any significant differences in echocardiographic parameters and clinical outcomes at 6-month follow-up. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30201 - Cardiac and Cardiovascular systems
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
cor et Vasa
ISSN
0010-8650
e-ISSN
1803-7712
Svazek periodika
60
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
10
Strana od-do
„E367“-„E376“
Kód UT WoS článku
000442902500005
EID výsledku v databázi Scopus
2-s2.0-85037999261