Utilization of autologous superficial femoral vein graft in cases of infected prosthetic graft replacement and high infection-risk cases

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00108562" target="_blank" >RIV/00216224:14110/19:00108562 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/19:00075949

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Utilization of autologous superficial femoral vein graft in cases of infected prosthetic graft replacement and high infection-risk cases

Popis výsledku v původním jazyce

Introduction: Aortic prosthetic graft infection is one of the most severe complications in vascular surgery. Good results are reported for the replacement using autologous superficial femoral vein (SFV) graft. This extensive procedure might be complicated by acute mesenteric ischemia (AMI). The aim of the study was to evaluate the safety of the procedure and options of early postoperative mesenteric ischemia detection. Methods: A retrospective review of 64 cases in which we have used autologous SFV graft was performed. The serum levels of biomarkers of AMI were assessed in comparison to 40 elective aortic surgery cases. Results: Average follow-up was 46.6 +/- 33.0 months, 30-day mortality was 6.3 %. The specificity of currently studied biomarkers of AMI (procalcitonin, ischemia modified albumin, I-FAPB2, and D-lactate) was low. Conclusions: Our results support the use of SFV graft for the treatment of aortic graft infection. Early postoperative detection of AMI remains challenging.

Název v anglickém jazyce

Utilization of autologous superficial femoral vein graft in cases of infected prosthetic graft replacement and high infection-risk cases

Popis výsledku anglicky

Introduction: Aortic prosthetic graft infection is one of the most severe complications in vascular surgery. Good results are reported for the replacement using autologous superficial femoral vein (SFV) graft. This extensive procedure might be complicated by acute mesenteric ischemia (AMI). The aim of the study was to evaluate the safety of the procedure and options of early postoperative mesenteric ischemia detection. Methods: A retrospective review of 64 cases in which we have used autologous SFV graft was performed. The serum levels of biomarkers of AMI were assessed in comparison to 40 elective aortic surgery cases. Results: Average follow-up was 46.6 +/- 33.0 months, 30-day mortality was 6.3 %. The specificity of currently studied biomarkers of AMI (procalcitonin, ischemia modified albumin, I-FAPB2, and D-lactate) was low. Conclusions: Our results support the use of SFV graft for the treatment of aortic graft infection. Early postoperative detection of AMI remains challenging.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30212 - Surgery

Projekt

<a href="/cs/project/NV17-29701A" target="_blank" >NV17-29701A: Ischémií modifikovaný albumin a cirkulující mikroRNA jako nové technologie k monitorování tkáňové ischémie po cévních rekonstrukcích na břišní aortě</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů