Inflammatory bowel disease incidence in South Moravian Region (Czech Republic); 2002-2016

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00111079" target="_blank" >RIV/00216224:14110/19:00111079 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/19:00071769

Výsledek na webu

<a href="https://www.gastrojournal.org/article/S0016-5085(19)30218-5/fulltext?referrer=https%3A%2F%2Fwww.researchgate.net%2F" target="_blank" >https://www.gastrojournal.org/article/S0016-5085(19)30218-5/fulltext?referrer=https%3A%2F%2Fwww.researchgate.net%2F</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.gastro.2019.01.155" target="_blank" >10.1053/j.gastro.2019.01.155</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Inflammatory bowel disease incidence in South Moravian Region (Czech Republic); 2002-2016

Popis výsledku v původním jazyce

Inflammatory bowel disease is considered a global disease in the 21st century. Studies worldwide have shown an increase in incidence in paediatric population. The aim of the study was to detect the rising incidence of IBD in paediatric population (approximately 240 000) over a 15-year period in the South Moravian Region of the Czech Republic. Another objective was to characterize differences by sex, age and to determine the future projection of incidence of IBD in the region and, by extension, the whole Czech Republic. Methods In the Czech Republic, the treatment of paediatric IBD is centralized into hospitals that provide tertiary care. University Hospital of Brno is one of the gastroenterology centres that provides a complex treatment of IBD patients. We evaluated 321 consecutive paediatric IBD patients &lt; 19 years of age in the South Moravian region (one of the 14 regional units in the Czech Republic). They all had been diagnosed according to the relevant guidelines. Results We evaluated 321 patiens with IBD: 167 of them had Crohn’s disease (52.0%), 114 had ulcerative colitis (35.5%) and 40 were IBD-unclassified (12.5%). Among all the cases of IBD, 53.8% were males. The average age of a diagnosed person was 13.37 years (95%CI: 12.97-13.76) and the patients went an average of 7.59 months (95%CI: 6.15-9.03) between the first symptoms and the diagnosis. The overall incidence of IBD significantly increased from 2.84 per 100 000 person-years in 2002 to 12.54 per 100 000 person-years in 2016 (P = 0.012). Conclusions Our results show that the overal incidence of paediatric IBD is increasing. These data highlight the need for a further research to identify the possible risk factors of IBD development This work was supported by the Ministry of Health of the Czech Republic, grant nr. 16-31314A, 16-31765A and RVO (FnBr, 65269705).

Název v anglickém jazyce

Inflammatory bowel disease incidence in South Moravian Region (Czech Republic); 2002-2016

Popis výsledku anglicky

Inflammatory bowel disease is considered a global disease in the 21st century. Studies worldwide have shown an increase in incidence in paediatric population. The aim of the study was to detect the rising incidence of IBD in paediatric population (approximately 240 000) over a 15-year period in the South Moravian Region of the Czech Republic. Another objective was to characterize differences by sex, age and to determine the future projection of incidence of IBD in the region and, by extension, the whole Czech Republic. Methods In the Czech Republic, the treatment of paediatric IBD is centralized into hospitals that provide tertiary care. University Hospital of Brno is one of the gastroenterology centres that provides a complex treatment of IBD patients. We evaluated 321 consecutive paediatric IBD patients &lt; 19 years of age in the South Moravian region (one of the 14 regional units in the Czech Republic). They all had been diagnosed according to the relevant guidelines. Results We evaluated 321 patiens with IBD: 167 of them had Crohn’s disease (52.0%), 114 had ulcerative colitis (35.5%) and 40 were IBD-unclassified (12.5%). Among all the cases of IBD, 53.8% were males. The average age of a diagnosed person was 13.37 years (95%CI: 12.97-13.76) and the patients went an average of 7.59 months (95%CI: 6.15-9.03) between the first symptoms and the diagnosis. The overall incidence of IBD significantly increased from 2.84 per 100 000 person-years in 2002 to 12.54 per 100 000 person-years in 2016 (P = 0.012). Conclusions Our results show that the overal incidence of paediatric IBD is increasing. These data highlight the need for a further research to identify the possible risk factors of IBD development This work was supported by the Ministry of Health of the Czech Republic, grant nr. 16-31314A, 16-31765A and RVO (FnBr, 65269705).

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

30209 - Paediatrics

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů