Perfect date-the review of current research into molecular bases of mammalian fertilization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00114231" target="_blank" >RIV/00216224:14110/20:00114231 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/content/pdf/10.1007/s10815-019-01679-4.pdf" target="_blank" >https://link.springer.com/content/pdf/10.1007/s10815-019-01679-4.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10815-019-01679-4" target="_blank" >10.1007/s10815-019-01679-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Perfect date-the review of current research into molecular bases of mammalian fertilization

Popis výsledku v původním jazyce

Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.

Název v anglickém jazyce

Perfect date-the review of current research into molecular bases of mammalian fertilization

Popis výsledku anglicky

Fertilization is a multistep process during which two terminally differentiated haploid cells, an egg and a sperm, combine to produce a totipotent diploid zygote. In the early 1950s, it became possible to fertilize mammalian eggs in vitro and study the sequence of cellular and molecular events leading to embryo development. Despite all the achievements of assisted reproduction in the last four decades, remarkably little is known about the molecular aspects of human conception. Current fertility research in animal models is casting more light on the complexity of the process all our lives start with. This review article provides an update on the investigation of mammalian fertilization and highlights the practical implications of scientific discoveries in the context of human reproduction and reproductive medicine.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

<a href="/cs/project/GJ19-14990Y" target="_blank" >GJ19-14990Y: Ultrastrukturní znaky kvality lidských oocytů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Assisted Reproduction and Genetics

ISSN

1058-0468

e-ISSN

1573-7330

Svazek periodika

37

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

14

Strana od-do

243-256

Kód UT WoS článku

000507352700001

EID výsledku v databázi Scopus

2-s2.0-85077535765