Severe hyperuricemia in two children with acute gastroenteritis: answers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00115904" target="_blank" >RIV/00216224:14110/20:00115904 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/20:00073025

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s00467-020-04493-8" target="_blank" >https://link.springer.com/article/10.1007/s00467-020-04493-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00467-020-04493-8" target="_blank" >10.1007/s00467-020-04493-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Severe hyperuricemia in two children with acute gastroenteritis: answers

Popis výsledku v původním jazyce

Uric acid (UA) is the end product of purine catabolism in humanoids, since the hepatocyte enzyme uricase, which degrades UA to allantoin in other mammals, is completely inactive. Approximately 65–75% of the UA produced daily is excreted by the kidneys, while the remaining 25–35% exits in the stool. Homeostasis of UA is determined by the balance between production and excretion. Hyperuricemia is caused by all conditions associated with increased purine synthesis and degradation during excessive cell breakdown and follow-up catabolism of nucleic acids, or an inability of the kidneys and gastrointestinal tract relative to urate excretion and clearance. During childhood, it is important to evaluate age- and sex-related serum UA concentration with respect to reference values.

Název v anglickém jazyce

Severe hyperuricemia in two children with acute gastroenteritis: answers

Popis výsledku anglicky

Uric acid (UA) is the end product of purine catabolism in humanoids, since the hepatocyte enzyme uricase, which degrades UA to allantoin in other mammals, is completely inactive. Approximately 65–75% of the UA produced daily is excreted by the kidneys, while the remaining 25–35% exits in the stool. Homeostasis of UA is determined by the balance between production and excretion. Hyperuricemia is caused by all conditions associated with increased purine synthesis and degradation during excessive cell breakdown and follow-up catabolism of nucleic acids, or an inability of the kidneys and gastrointestinal tract relative to urate excretion and clearance. During childhood, it is important to evaluate age- and sex-related serum UA concentration with respect to reference values.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30209 - Paediatrics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pediatric Nephrology

ISSN

0931-041X

e-ISSN

1432-198X

Svazek periodika

35

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

1431-1435

Kód UT WoS článku

000513051100003

EID výsledku v databázi Scopus

2-s2.0-85079731448