Interim analysis of COVID-19 vaccine effectiveness against Severe Acute Respiratory Infection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F21%3A00123713" target="_blank" >RIV/00216224:14110/21:00123713 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.ecdc.europa.eu/sites/default/files/documents/TRP-20211004-1860_0.pdf" target="_blank" >https://www.ecdc.europa.eu/sites/default/files/documents/TRP-20211004-1860_0.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Interim analysis of COVID-19 vaccine effectiveness against Severe Acute Respiratory Infection

Popis výsledku v původním jazyce

This document reports the first interim pooled estimates from the ECDC study of COVID-19 vaccine effectiveness (VE), conducted through the implementation of a multi-country approach using the Core protocol for ECDC studies of COVID-19 vaccine effectiveness against hospitalisation with Severe Acute Respiratory Infection laboratoryconfirmed with SARS-CoV-2, version 1.0 [1].Interim pooled estimates of COVID-19 VE were calculated for all COVID-19 vaccines deployed, including the COVID-19 mRNA vaccine Comirnaty (Pfizer/BioNTech), among hospitalised individuals aged 65 years and older with SARI due to laboratory-confirmed SARS-CoV-2, across EU/EEA participating countries. The study is currently ongoing and interim analyses will be conducted on a regular basis, with results updated as relevant. Pooled estimates are from patients recruited across several hospital study sites in the EU/EEA. These interim estimates mainly cover the pre-Delta period, adding further evidence to the existing literature on COVID-19 VE during this time. While VE estimates are important to inform vaccine recommendations, it is also important to ensure that robust methods were used to produce these estimates. Hence, this document presents a detailed description of both the methods used and the characteristics of the cases and controls enrolled in the study. For more details regarding the methods of the study, reference should be made to the core ECDC protocol [1].

Název v anglickém jazyce

Interim analysis of COVID-19 vaccine effectiveness against Severe Acute Respiratory Infection

Popis výsledku anglicky

This document reports the first interim pooled estimates from the ECDC study of COVID-19 vaccine effectiveness (VE), conducted through the implementation of a multi-country approach using the Core protocol for ECDC studies of COVID-19 vaccine effectiveness against hospitalisation with Severe Acute Respiratory Infection laboratoryconfirmed with SARS-CoV-2, version 1.0 [1].Interim pooled estimates of COVID-19 VE were calculated for all COVID-19 vaccines deployed, including the COVID-19 mRNA vaccine Comirnaty (Pfizer/BioNTech), among hospitalised individuals aged 65 years and older with SARI due to laboratory-confirmed SARS-CoV-2, across EU/EEA participating countries. The study is currently ongoing and interim analyses will be conducted on a regular basis, with results updated as relevant. Pooled estimates are from patients recruited across several hospital study sites in the EU/EEA. These interim estimates mainly cover the pre-Delta period, adding further evidence to the existing literature on COVID-19 VE during this time. While VE estimates are important to inform vaccine recommendations, it is also important to ensure that robust methods were used to produce these estimates. Hence, this document presents a detailed description of both the methods used and the characteristics of the cases and controls enrolled in the study. For more details regarding the methods of the study, reference should be made to the core ECDC protocol [1].

Druh

V_souhrn - Souhrnná výzkumná zpráva

CEP obor

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OECD FORD obor

30230 - Other clinical medicine subjects

Projekt

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Návaznosti

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Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Počet stran výsledku

15

Místo vydání

Stockholm

Název nakladatele resp. objednatele

ECDC European Centre for Disease Prevention and Control

Verze

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