LONG-TERM OUTCOMES OF CONVERGENT ABLATION FOR PERSISTENT ANDLONG-STANDING PERSISTENT ATRIALFIBRILLATION

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F23%3A00132320" target="_blank" >RIV/00216224:14110/23:00132320 - isvavai.cz</a>

Výsledek na webu

<a href="https://e-coretvasa.cz/incpdfs/inf-990000-1100_10_004.pdf" target="_blank" >https://e-coretvasa.cz/incpdfs/inf-990000-1100_10_004.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

LONG-TERM OUTCOMES OF CONVERGENT ABLATION FOR PERSISTENT ANDLONG-STANDING PERSISTENT ATRIALFIBRILLATION

Popis výsledku v původním jazyce

Single-stage hybrid radiofrequency ablation (hRFA) com- bines endoscopic epicardial and catheter endocardial ab- lation as a treatment for otherwise unsolvable long-term persistent atrial fibrillation (AF). We present the evalua- tion of outcomes at one center following hRFA. Methods: A total of 60 patients aged 61.59±7.8 years un- derwent single-stage hRFA from April 2016 to March 2022 at the Centre for Cardiovascular and Transplant Surgery and St. Anne’s University Hospital Brno, Czech Republic. This method includes thoracoscopic isolation of pulmo- nary veins and box lesion creation followed by catheter based verifi cation of the effect of the surgical portion of the procedure in one procedure. Baseline and follow-up data were prospectively record- ed during scheduled follow-up. The primary outcome was freedom from AF on/off anti-arrhythmic drugs after a 12-month follow-up. Secondary outcomes included freedom from AF over the entire follow-up, freedom from anti-arrhythmic drugs, and freedom from any atrial arrhythmias, repeat ablation, and complications. Results: The median duration of the procedure was 237 minutes and the median duration of hospitalization was 10 days. At the end of the procedure, 60 patients (100%) had sinus rhythm (SR). At the first follow-up after three months of surgery, 49 of 57 (85.9%) patients were AF-free, at the 6-month follow-up, 46 of 56 patients (82.0%) were AF-free. At the 12-month visit 41 of 55 (76.4%) patients were AF-free and at 24 months were 33 of the initial 53 patients (62.2%) event free. Seven patients were lost to follow-up. Acute complications were 1× left atrial perforation resolved successfully by suture and 1× transient ischaemic attack without permanent sequelae. Late complications involved one massive pulmonary embolization and an atrioesophageal fistula. There was no periprocedural myocardial infarction or stroke with permanent sequelae. Conclusion: Single stage hybrid radiofrequency ablation is an effective and relatively safe mini-invasive method of treatment for long-term persistent atrial fibrillation with extremely enlarged LA

Název v anglickém jazyce

LONG-TERM OUTCOMES OF CONVERGENT ABLATION FOR PERSISTENT ANDLONG-STANDING PERSISTENT ATRIALFIBRILLATION

Popis výsledku anglicky

Single-stage hybrid radiofrequency ablation (hRFA) com- bines endoscopic epicardial and catheter endocardial ab- lation as a treatment for otherwise unsolvable long-term persistent atrial fibrillation (AF). We present the evalua- tion of outcomes at one center following hRFA. Methods: A total of 60 patients aged 61.59±7.8 years un- derwent single-stage hRFA from April 2016 to March 2022 at the Centre for Cardiovascular and Transplant Surgery and St. Anne’s University Hospital Brno, Czech Republic. This method includes thoracoscopic isolation of pulmo- nary veins and box lesion creation followed by catheter based verifi cation of the effect of the surgical portion of the procedure in one procedure. Baseline and follow-up data were prospectively record- ed during scheduled follow-up. The primary outcome was freedom from AF on/off anti-arrhythmic drugs after a 12-month follow-up. Secondary outcomes included freedom from AF over the entire follow-up, freedom from anti-arrhythmic drugs, and freedom from any atrial arrhythmias, repeat ablation, and complications. Results: The median duration of the procedure was 237 minutes and the median duration of hospitalization was 10 days. At the end of the procedure, 60 patients (100%) had sinus rhythm (SR). At the first follow-up after three months of surgery, 49 of 57 (85.9%) patients were AF-free, at the 6-month follow-up, 46 of 56 patients (82.0%) were AF-free. At the 12-month visit 41 of 55 (76.4%) patients were AF-free and at 24 months were 33 of the initial 53 patients (62.2%) event free. Seven patients were lost to follow-up. Acute complications were 1× left atrial perforation resolved successfully by suture and 1× transient ischaemic attack without permanent sequelae. Late complications involved one massive pulmonary embolization and an atrioesophageal fistula. There was no periprocedural myocardial infarction or stroke with permanent sequelae. Conclusion: Single stage hybrid radiofrequency ablation is an effective and relatively safe mini-invasive method of treatment for long-term persistent atrial fibrillation with extremely enlarged LA

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

Projekt

<a href="/cs/project/LX22NPO5104" target="_blank" >LX22NPO5104: Národní institut pro výzkum metabolických a kardiovaskulárních onemocnění</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů