Determinants and Reliability of the Ambulatory Arterial Stiffness Index, AASI

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F24%3A00138684" target="_blank" >RIV/00216224:14110/24:00138684 - isvavai.cz</a>

Výsledek na webu

<a href="https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2024.pdf" target="_blank" >https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2024.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5817/CZ.MUNI.M280-0669-2024-2" target="_blank" >10.5817/CZ.MUNI.M280-0669-2024-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determinants and Reliability of the Ambulatory Arterial Stiffness Index, AASI

Popis výsledku v původním jazyce

The Ambulatory Arterial Stiffness Index (AASI) was introduced as an easily implemented way to non-invasively assess arterial stiffness from 24-hour ambulatory blood pressure monitoring (ABPM) records. After a brief review of the literature, this investigation considers ABPM records from two clinically healthy populations to compute the AASI and assess its major determinants. The 7-day/24- hour ABPM records collected in one of the two studies served to determine the extent of day-to-day variability in the AASI estimation. In the other study, age, body mass index (BMI), systolic (S) BP MESOR, and pulse pressure (PP) correlated positively with AASI, while the magnitude (extent of predictable daily change) of SBP and the 24-hour amplitude of diastolic (D) BP correlated negatively with AASI. Although AASI computed on separate days correlates well with its value estimated from the entire 7-day record, the day-to-day variation in its estimate is quite large. The relatively large difference in estimated average AASI between the two studies, which included seemingly similar populations, can be accounted for by taking into consideration the small differences in all determinants of the AASI existing between the two samples. Novel findings from this investigation are the effect on AASI of (1) a misaligned circadian BP rhythm, and of (2) a sparser nighttime vs. daytime sampling. Although our results agree with published results, the large uncertainty associated with the estimation of AASI may limit its clinical usefulness in guiding the treatment of individual patients.

Název v anglickém jazyce

Determinants and Reliability of the Ambulatory Arterial Stiffness Index, AASI

Popis výsledku anglicky

The Ambulatory Arterial Stiffness Index (AASI) was introduced as an easily implemented way to non-invasively assess arterial stiffness from 24-hour ambulatory blood pressure monitoring (ABPM) records. After a brief review of the literature, this investigation considers ABPM records from two clinically healthy populations to compute the AASI and assess its major determinants. The 7-day/24- hour ABPM records collected in one of the two studies served to determine the extent of day-to-day variability in the AASI estimation. In the other study, age, body mass index (BMI), systolic (S) BP MESOR, and pulse pressure (PP) correlated positively with AASI, while the magnitude (extent of predictable daily change) of SBP and the 24-hour amplitude of diastolic (D) BP correlated negatively with AASI. Although AASI computed on separate days correlates well with its value estimated from the entire 7-day record, the day-to-day variation in its estimate is quite large. The relatively large difference in estimated average AASI between the two studies, which included seemingly similar populations, can be accounted for by taking into consideration the small differences in all determinants of the AASI existing between the two samples. Novel findings from this investigation are the effect on AASI of (1) a misaligned circadian BP rhythm, and of (2) a sparser nighttime vs. daytime sampling. Although our results agree with published results, the large uncertainty associated with the estimation of AASI may limit its clinical usefulness in guiding the treatment of individual patients.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Noninvasive methods in cardiology 2024

ISBN

9788028006686

ISSN

—

e-ISSN

—

Počet stran výsledku

13

Strana od-do

19-31

Název nakladatele

Masaryk University Press

Místo vydání

Masaryk University Press Brno

Místo konání akce

Masaryk University Press Brno

Datum konání akce

1. 1. 2024

Typ akce podle státní příslušnosti

CST - Celostátní akce

Kód UT WoS článku

—