Chirurgická rekonstrukce poškozeného brachiálního plexu a experimentální reinervace přes acelulární nervový štěp

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F98%3A00028148" target="_blank" >RIV/00216224:14110/98:00028148 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft

Popis výsledku v původním jazyce

Thirty six patients with brachial plexus injury have been operated on. Results were very good in the case of infraganglionic lesions in 15 patients. Fair and good results were obtained in 72% of 18 patients with neurotization procedure of musculocutaneous and axillary nerves. Transfer of latissimus dorsi muscle instead of the biceps muscle was successful in another t cases. In the experimental animals the acellular nerve grafts was used to restore a functional reinnervation of the biceps brachii muscleby the motoneuron pool of the cervical spinal cord.. The musculocutaneous nerve stump was sutured with acellular nerve graft, the opposite end of which was inserted into the cervical spinal cord up to the avulsed C5 ventral root. Behavioural, electrophysiological as well as morphological methods proved the reconnection of the spinal motor neurons with the muscle end plates. Our results demonstrate that the acellular nerve graft repopulated by Schwann cells migrating from the nerve stump,

Název v anglickém jazyce

Surgical management of brachial plexus injuries and the experimental reinnervation of the biceps muscle by the spinal motoneurons through acellular nerve graft

Popis výsledku anglicky

Thirty six patients with brachial plexus injury have been operated on. Results were very good in the case of infraganglionic lesions in 15 patients. Fair and good results were obtained in 72% of 18 patients with neurotization procedure of musculocutaneous and axillary nerves. Transfer of latissimus dorsi muscle instead of the biceps muscle was successful in another t cases. In the experimental animals the acellular nerve grafts was used to restore a functional reinnervation of the biceps brachii muscleby the motoneuron pool of the cervical spinal cord.. The musculocutaneous nerve stump was sutured with acellular nerve graft, the opposite end of which was inserted into the cervical spinal cord up to the avulsed C5 ventral root. Behavioural, electrophysiological as well as morphological methods proved the reconnection of the spinal motor neurons with the muscle end plates. Our results demonstrate that the acellular nerve graft repopulated by Schwann cells migrating from the nerve stump,

Druh

D - Stať ve sborníku

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/IZ2605" target="_blank" >IZ2605: Alternativní metody překonávání defektu poškozeného nervu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

1998

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

7th Congress IFSSH

ISBN

88-323-0524-0

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

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Název nakladatele

Monduzzi Editore

Místo vydání

Bologna

Místo konání akce

24.-28.5. 1998 Vancouver

Datum konání akce

1. 1. 1998

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000077111100103