Spatiotemporal Control of the Formation of Luminescent Lanthanide Complexes in Liposome-Based Nanoreactors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F25%3A00142122" target="_blank" >RIV/00216224:14160/25:00142122 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202510471" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/anie.202510471</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/anie.202510471" target="_blank" >10.1002/anie.202510471</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spatiotemporal Control of the Formation of Luminescent Lanthanide Complexes in Liposome-Based Nanoreactors

Popis výsledku v původním jazyce

The controlled mass transfer across compartmentalised environments in synthetic nanoreactors is essential for enhancing precise spatiotemporal manipulation of chemical transformations within confined spaces. In this study, we present a strategy that integrates a synthetic anion transporter in liposome-based nanoreactors, allowing for spatiotemporal control over the formation of metal-organic complexes in liposomes. This approach enables us to effectively modulate the assembly of luminescent lanthanide-benzenedicarboxylate nanostructures. Fluorescence studies demonstrate that the reaction rate can be customised by varying the anion transporter concentration, which dictates the rate of entry of the carboxylate ligand. Changes in the morphology of the liposome nanoreactors due to the assisted transmembrane transport of benzenedicarboxylate were investigated using cryo-TEM and time-resolved SAXS measurements, which revealed a structural transformation of the lipid bilayer during the complex formation. Our findings provide a novel platform for exploring coordination chemistry in nanoscale confinements, opening avenues for the design of biohybrid materials.

Název v anglickém jazyce

Spatiotemporal Control of the Formation of Luminescent Lanthanide Complexes in Liposome-Based Nanoreactors

Popis výsledku anglicky

The controlled mass transfer across compartmentalised environments in synthetic nanoreactors is essential for enhancing precise spatiotemporal manipulation of chemical transformations within confined spaces. In this study, we present a strategy that integrates a synthetic anion transporter in liposome-based nanoreactors, allowing for spatiotemporal control over the formation of metal-organic complexes in liposomes. This approach enables us to effectively modulate the assembly of luminescent lanthanide-benzenedicarboxylate nanostructures. Fluorescence studies demonstrate that the reaction rate can be customised by varying the anion transporter concentration, which dictates the rate of entry of the carboxylate ligand. Changes in the morphology of the liposome nanoreactors due to the assisted transmembrane transport of benzenedicarboxylate were investigated using cryo-TEM and time-resolved SAXS measurements, which revealed a structural transformation of the lipid bilayer during the complex formation. Our findings provide a novel platform for exploring coordination chemistry in nanoscale confinements, opening avenues for the design of biohybrid materials.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ISSN

1521-3773

e-ISSN

1521-3773

Svazek periodika

64

Číslo periodika v rámci svazku

45

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

10

Strana od-do

202510471

Kód UT WoS článku

001570229900001

EID výsledku v databázi Scopus

2-s2.0-105015830093