Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F25%3A00142912" target="_blank" >RIV/00216224:14160/25:00142912 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf" target="_blank" >https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics

Popis výsledku v původním jazyce

Natural mucoadhesive polymers, such as sodium alginate, have garnered significant research attention for their beneficial properties in developing modern dosage forms, including vaginal drug delivery for infections treatment. Sodium alginate can form polymer hydrogel particles through external ionic gelation with safe cross-linking ions like Ca2+ [1]. These polymer carriers can serve as vehicles to incorporate biologically active natural substances derived from plant sources such as thymol, eugenol, and carvacrol. Their combinations may exhibit synergistic effects that hold promise in combating infectious diseases [2]. By integrating these substances into mucoadhesive polymers, we can leverage their effects when applied to mucous membranes. This study will explore the antimicrobial synergistic impact of these aforementioned phytotherapeutics against Escherichia coli (E. coli).

Název v anglickém jazyce

Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics

Popis výsledku anglicky

Natural mucoadhesive polymers, such as sodium alginate, have garnered significant research attention for their beneficial properties in developing modern dosage forms, including vaginal drug delivery for infections treatment. Sodium alginate can form polymer hydrogel particles through external ionic gelation with safe cross-linking ions like Ca2+ [1]. These polymer carriers can serve as vehicles to incorporate biologically active natural substances derived from plant sources such as thymol, eugenol, and carvacrol. Their combinations may exhibit synergistic effects that hold promise in combating infectious diseases [2]. By integrating these substances into mucoadhesive polymers, we can leverage their effects when applied to mucous membranes. This study will explore the antimicrobial synergistic impact of these aforementioned phytotherapeutics against Escherichia coli (E. coli).

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů