Impact of rational antibiotic usage on occurrence of vancomycin-resistant enterococci in hematological patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F01%3A00004694" target="_blank" >RIV/00216224:14310/01:00004694 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Impact of rational antibiotic usage on occurrence of vancomycin-resistant enterococci in hematological patients

Popis výsledku v původním jazyce

Objectives: The hematological patients are jeopardised by staphylococci and enterococci from the group of Gram-positive bacteria. Especially great danger for the hematological patients are the vancomycin-resistant enterococci that may be a very big therapeutic problem in some cases. Methods: Enterococci were isolated from clinical samples of patients hospitalised at the Department of Hemato-oncology of University Hospital in Olomouc, Czech Republic, during period 1995-2000. The usage of antibiotics wasexpressed as the number of defined daily doses (DDD) per 1000 bed-days (RDDD) during the observation periods according to the following formula: RDDD=DDD x 1000/NB (NB=number of bed-days). To evaluate the selection pressure of antibiotics and occurrenceof VRE, we used each six-month interval from 1st half of 1997 to 1st half of 2000. Results: In total, 1918 strains were isolated in the Department of Hemato-oncology, from which 138 (7.2%) were identified as VRE. The percentage of VRE in

Název v anglickém jazyce

Impact of rational antibiotic usage on occurrence of vancomycin-resistant enterococci in hematological patients

Popis výsledku anglicky

Objectives: The hematological patients are jeopardised by staphylococci and enterococci from the group of Gram-positive bacteria. Especially great danger for the hematological patients are the vancomycin-resistant enterococci that may be a very big therapeutic problem in some cases. Methods: Enterococci were isolated from clinical samples of patients hospitalised at the Department of Hemato-oncology of University Hospital in Olomouc, Czech Republic, during period 1995-2000. The usage of antibiotics wasexpressed as the number of defined daily doses (DDD) per 1000 bed-days (RDDD) during the observation periods according to the following formula: RDDD=DDD x 1000/NB (NB=number of bed-days). To evaluate the selection pressure of antibiotics and occurrenceof VRE, we used each six-month interval from 1st half of 1997 to 1st half of 2000. Results: In total, 1918 strains were isolated in the Department of Hemato-oncology, from which 138 (7.2%) were identified as VRE. The percentage of VRE in

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA301%2F99%2FD075" target="_blank" >GA301/99/D075: Genotypová diagnostika a typizace klinicky významných koaguláza negativních stafylokoků</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2001

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Microbiology and Infection

ISSN

1469-0691

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

Suppl 1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

91

Kód UT WoS článku

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EID výsledku v databázi Scopus

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