Molecular typing of exfoliative toxin-producing <I>Staphylococcus aureus</I> strains involved in epidermolytic infections

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F03%3A00008577" target="_blank" >RIV/00216224:14310/03:00008577 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/03:00009834

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Molecular typing of exfoliative toxin-producing <I>Staphylococcus aureus</I> strains involved in epidermolytic infections

Popis výsledku v původním jazyce

Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affectedby an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted inthe determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged imp

Název v anglickém jazyce

Molecular typing of exfoliative toxin-producing <I>Staphylococcus aureus</I> strains involved in epidermolytic infections

Popis výsledku anglicky

Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affectedby an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted inthe determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged imp

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Medical Microbiology

ISSN

1438-4221

e-ISSN

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Svazek periodika

292

Číslo periodika v rámci svazku

7-8

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

541

Kód UT WoS článku

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EID výsledku v databázi Scopus

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