Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F03%3A00019255" target="_blank" >RIV/00216224:14310/03:00019255 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state

Popis výsledku v původním jazyce

The biological half-life of bromide, as substituting for sodium or chloride, was investigated with the aid of the radionuclide 82Br in lactating and non-lactating female rats as well as in young rats of varying ages. Non-weaned young rats (12 d) had thehighest half-life (269 h) and lactating dams the lowest (44 h). The determined values demonstrated that non-weaned young apparently conserve Na, while lactating dams, due to their large food intake, waste Na. The parallel course of the excretion rates ofsodium and bromide ions was demonstrated in adult male rats administered simultaneously with 24Na-sodium chloride and 82Br-bromide. These excretion rates were inversely proportional to the magnitude of sodium intake in the animals.

Název v anglickém jazyce

Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state

Popis výsledku anglicky

The biological half-life of bromide, as substituting for sodium or chloride, was investigated with the aid of the radionuclide 82Br in lactating and non-lactating female rats as well as in young rats of varying ages. Non-weaned young rats (12 d) had thehighest half-life (269 h) and lactating dams the lowest (44 h). The determined values demonstrated that non-weaned young apparently conserve Na, while lactating dams, due to their large food intake, waste Na. The parallel course of the excretion rates ofsodium and bromide ions was demonstrated in adult male rats administered simultaneously with 24Na-sodium chloride and 82Br-bromide. These excretion rates were inversely proportional to the magnitude of sodium intake in the animals.

Druh

D - Stať ve sborníku

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Trace Elements in Human: New Perspectives (Ermidou-Pollet S., Pollet S., eds.) [IF=n.a.]

ISBN

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ISSN

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e-ISSN

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Počet stran výsledku

9

Strana od-do

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Název nakladatele

University of Athens

Místo vydání

Athens

Místo konání akce

Athens (Greece)

Datum konání akce

1. 1. 2003

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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