Přímý a nepřímý průkaz chlamydia pneumoniae u pacientů s významnou stenózou a. carotis aterosklerotického původu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00021372" target="_blank" >RIV/00216224:14310/04:00021372 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Direct and indirect evidence of Chlamydia pneumoniae in patients with significant stenosis of a. carotis of atherosclerotic origin

Popis výsledku v původním jazyce

The aim of this study was to ascertain the role of Chlamydia pneumoniae in the pathogenesis of significant carotid atherosclerotic stenosis in thirty patients (25 male and 5 female, 67.5 years old on avŹerage) through both direct and indirect methods. Direct evidence of polymerase chain reaction (PCR) in the DNA product Chlamydia pneumoniae in the atherosclerotic plaque obtained during the operaŹtion of a. carotis was positive in 56.7% of the patients. Blood sera were analysed using enzyme immuŹnoassay(ELISA) for the detection of species-specific antibodies in the immunoglobulin classes IgA, IgG and IgM against Chlamydia pneumoniae, and ELISA for the detection of antibodies in the class IgG to chlamydial heat shock protein (cHSP60). Species-specific antibodies of Chlamydia pneumoniae in the IgA class were detected in 60 % of the patients, in the IgG class in 86.7 %, and in the IgM class in 3.3 %. Chlamydial heat shock protein antibodies were detected in 56.7% of the patients. The resu

Název v anglickém jazyce

Direct and indirect evidence of Chlamydia pneumoniae in patients with significant stenosis of a. carotis of atherosclerotic origin

Popis výsledku anglicky

The aim of this study was to ascertain the role of Chlamydia pneumoniae in the pathogenesis of significant carotid atherosclerotic stenosis in thirty patients (25 male and 5 female, 67.5 years old on avŹerage) through both direct and indirect methods. Direct evidence of polymerase chain reaction (PCR) in the DNA product Chlamydia pneumoniae in the atherosclerotic plaque obtained during the operaŹtion of a. carotis was positive in 56.7% of the patients. Blood sera were analysed using enzyme immuŹnoassay(ELISA) for the detection of species-specific antibodies in the immunoglobulin classes IgA, IgG and IgM against Chlamydia pneumoniae, and ELISA for the detection of antibodies in the class IgG to chlamydial heat shock protein (cHSP60). Species-specific antibodies of Chlamydia pneumoniae in the IgA class were detected in 60 % of the patients, in the IgG class in 86.7 %, and in the IgM class in 3.3 %. Chlamydial heat shock protein antibodies were detected in 56.7% of the patients. The resu

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scripta medica

ISSN

1211-3395

e-ISSN

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Svazek periodika

77

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

173-180

Kód UT WoS článku

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EID výsledku v databázi Scopus

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