Aktivace Ah receptoru huminovými látkami

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F05%3A00014614" target="_blank" >RIV/00216224:14310/05:00014614 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Activation of AH-receptor by humic substances

Popis výsledku v původním jazyce

Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA),fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progressionof endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR). We tested alkali solution of a commercially available hum

Název v anglickém jazyce

Activation of AH-receptor by humic substances

Popis výsledku anglicky

Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA),fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progressionof endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR). We tested alkali solution of a commercially available hum

Druh

D - Stať ve sborníku

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

<a href="/cs/project/GP525%2F05%2FP160" target="_blank" >GP525/05/P160: In vitro modely pro studium endokrinní disrupce - účinky tradičních a nových typů persistentních organických polutantů</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Joint Conference of Scandinavian Society of Cell Toxicology and Estonian Society of Toxicology

ISBN

9949-13-297-5

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

102-102

Název nakladatele

ETS-SSCT

Místo vydání

Tallinn, Estonsko

Místo konání akce

Toila. Estonsko

Datum konání akce

20. 10. 2005

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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