Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00016309" target="_blank" >RIV/00216224:14310/06:00016309 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

Popis výsledku v původním jazyce

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both byindividual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 5

Název v anglickém jazyce

Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

Popis výsledku anglicky

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both byindividual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 5

Druh

O - Ostatní výsledky

CEP obor

DK - Kontaminace a dekontaminace půdy včetně pesticidů

OECD FORD obor

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Projekt

<a href="/cs/project/GP525%2F04%2FP159" target="_blank" >GP525/04/P159: Vliv nově rozpoznávaných prioritních perzistentních organických polutantů (POPs) na organismy v půdním ekosystému</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů