Metazoan parasites and balancing selection at MHC class IIB genes in the wild populations of freshwater cyprinid fish (Leuciscus cephalus)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00042632" target="_blank" >RIV/00216224:14310/09:00042632 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Metazoan parasites and balancing selection at MHC class IIB genes in the wild populations of freshwater cyprinid fish (Leuciscus cephalus)

Popis výsledku v původním jazyce

Major histocompatibility complex (MHC) genes are highly polymorphic. The high level of nucleotide and allelic diversity is maintained by balancing or parasite driven selection. In this study, we investigated the metazoan parasite load and MHC diversity in fifteen chub (Leuciscus cephalus) populations in Europe. The exon 2 of DAB genes (MHC class IIB) was selected for sequence analysis considering that this part of DAB genes encodes the major parts of the PBR (peptide binding regions) as the most polymorphic parts in many class II genes. Likewise, twelve microsatellite loci were studied to elucidate the role of neutral evolutionary processes on MHC variability. Spearman correlation analysis revealed an influence of geographic distance and genetic distance on similarity between metazoan parasite communities. Within individual fish the highest mean variability in parasite abundance and mean species parasite richness were associated with the maximal number of alleles.

Název v anglickém jazyce

Metazoan parasites and balancing selection at MHC class IIB genes in the wild populations of freshwater cyprinid fish (Leuciscus cephalus)

Popis výsledku anglicky

Major histocompatibility complex (MHC) genes are highly polymorphic. The high level of nucleotide and allelic diversity is maintained by balancing or parasite driven selection. In this study, we investigated the metazoan parasite load and MHC diversity in fifteen chub (Leuciscus cephalus) populations in Europe. The exon 2 of DAB genes (MHC class IIB) was selected for sequence analysis considering that this part of DAB genes encodes the major parts of the PBR (peptide binding regions) as the most polymorphic parts in many class II genes. Likewise, twelve microsatellite loci were studied to elucidate the role of neutral evolutionary processes on MHC variability. Spearman correlation analysis revealed an influence of geographic distance and genetic distance on similarity between metazoan parasite communities. Within individual fish the highest mean variability in parasite abundance and mean species parasite richness were associated with the maximal number of alleles.

Druh

O - Ostatní výsledky

CEP obor

EH - Ekologie – společenstva

OECD FORD obor

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Projekt

<a href="/cs/project/LC522" target="_blank" >LC522: ICHTYOPARAZITOLOGIE - centrum základního výzkumu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů