Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050059" target="_blank" >RIV/00216224:14310/11:00050059 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana

Popis výsledku v původním jazyce

There are many new insights about how the animal sense for geomagnetic field might work ? whether based on magnetic particles in tissues or on light perception in visual pathway - but the exact mechanism of reception and transmission has not yet been clarified. In our work, we addressed the question of the role of Cryptochrome in compass sense of insects. Cryptochromes (CRYs) are molecules found in retina both vertebrates and invertebrates - among other things directly involved in controlling of circadian rhythms. In our tests, we worked with a cockroach Periplaneta americana which has the only vertebrate-like type of cryptochrom, CRY2. We combined molecular genetic approaches (RNAi gene silencing) with a behavioral assay (studying movement activity ofcockroaches in changing magnetic field). Cockroaches were injected with CRY dsRNA and, 15 days later, they underwent an assay. Treated animals not only lost their circadian rhythmicity, but they were not able to perceive the magnetic fie

Název v anglickém jazyce

Cryptochrome 2 necessary for magnetosensitivity of American cockroach P. americana

Popis výsledku anglicky

There are many new insights about how the animal sense for geomagnetic field might work ? whether based on magnetic particles in tissues or on light perception in visual pathway - but the exact mechanism of reception and transmission has not yet been clarified. In our work, we addressed the question of the role of Cryptochrome in compass sense of insects. Cryptochromes (CRYs) are molecules found in retina both vertebrates and invertebrates - among other things directly involved in controlling of circadian rhythms. In our tests, we worked with a cockroach Periplaneta americana which has the only vertebrate-like type of cryptochrom, CRY2. We combined molecular genetic approaches (RNAi gene silencing) with a behavioral assay (studying movement activity ofcockroaches in changing magnetic field). Cockroaches were injected with CRY dsRNA and, 15 days later, they underwent an assay. Treated animals not only lost their circadian rhythmicity, but they were not able to perceive the magnetic fie

Druh

O - Ostatní výsledky

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/GC206%2F07%2FJ041" target="_blank" >GC206/07/J041: Neurální podstata magnetorecepce hmyzu.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů