Study of ergosterol signal pathway

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050628" target="_blank" >RIV/00216224:14310/11:00050628 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Study of ergosterol signal pathway

Popis výsledku v původním jazyce

Ergosterol principal compound of the fungal plasma membrane belongs to the group of elicitors called non-specific elicitors whose not differ in their effects on different cultivars within a plant species. It triggers a defence reaction in tobacco and tomato cells manifested by active oxygen species synthesis and changes of ion fluxes. Further production of the phytoalexin capsidiol and pathogenesis related proteins expression was observed. Even though some steps of signalling pathway including phospholipase A2 protein kinase C and intracellular calcium were proposed up today activation mechanism was not elucidate. But it is assumed role of some specific binding partner or lipid rafts. Here we have attempted to elucidate in more details of the signal pathway elicited by ergosterol. Therefore we focused on study of calcium signalling by using fluorescence confocal microscopy and specific inhibitors.

Název v anglickém jazyce

Study of ergosterol signal pathway

Popis výsledku anglicky

Ergosterol principal compound of the fungal plasma membrane belongs to the group of elicitors called non-specific elicitors whose not differ in their effects on different cultivars within a plant species. It triggers a defence reaction in tobacco and tomato cells manifested by active oxygen species synthesis and changes of ion fluxes. Further production of the phytoalexin capsidiol and pathogenesis related proteins expression was observed. Even though some steps of signalling pathway including phospholipase A2 protein kinase C and intracellular calcium were proposed up today activation mechanism was not elucidate. But it is assumed role of some specific binding partner or lipid rafts. Here we have attempted to elucidate in more details of the signal pathway elicited by ergosterol. Therefore we focused on study of calcium signalling by using fluorescence confocal microscopy and specific inhibitors.

Druh

O - Ostatní výsledky

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů