Cloning and characterization of novel jacalin-related lectin from Aspergillus fumigatus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00057533" target="_blank" >RIV/00216224:14310/12:00057533 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Cloning and characterization of novel jacalin-related lectin from Aspergillus fumigatus

Popis výsledku v původním jazyce

Lectins are proteins or glycoproteins of non-immune origin which recognize and bind reversibly to diverse sugar structures. They are involved in recognition events in a variety of biological processes, such as regulation of cell cycle, targeting of cells, host-pathogen interactions, plant defense and cell differentiation. Jacalin-related proteins (JRPs) represent a family of lectins that are structurally related to jacalin, a well-known plant seed lectin isolated from jack fruit. JRPs are widespread among plants, while only few members have been found in fungi so far. Despite high sequence similarity among jacalin-related proteins, they differ from each other with respect to carbohydrate-binding preferences. Aspergillus fumigatus is an ubiquitous saprophytic mold and opportunistic human pathogen responsible for severe infections in cystic fibrosis and lung transplant patients.

Název v anglickém jazyce

Cloning and characterization of novel jacalin-related lectin from Aspergillus fumigatus

Popis výsledku anglicky

Lectins are proteins or glycoproteins of non-immune origin which recognize and bind reversibly to diverse sugar structures. They are involved in recognition events in a variety of biological processes, such as regulation of cell cycle, targeting of cells, host-pathogen interactions, plant defense and cell differentiation. Jacalin-related proteins (JRPs) represent a family of lectins that are structurally related to jacalin, a well-known plant seed lectin isolated from jack fruit. JRPs are widespread among plants, while only few members have been found in fungi so far. Despite high sequence similarity among jacalin-related proteins, they differ from each other with respect to carbohydrate-binding preferences. Aspergillus fumigatus is an ubiquitous saprophytic mold and opportunistic human pathogen responsible for severe infections in cystic fibrosis and lung transplant patients.

Druh

O - Ostatní výsledky

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů