Life cycle of Cryptosporidium muris in experimental conditions
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00058216" target="_blank" >RIV/00216224:14310/12:00058216 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Life cycle of Cryptosporidium muris in experimental conditions
Popis výsledku v původním jazyce
Cryptosporidia (Apicomplexa) have been recently recognized as one of the most ubiquitous parasites infecting gastrointestinal and respiratory tract of vertebrates. Localization of cryptosporidian developmental stages in the host epithelium has been the subject of extensive speculation for many years. Our published data support the term epicellular to reflect the cryptosporidian localization, rather than the term intracellular extracytoplasmic, used throughout the literature. Due to its peculiar localization, Cryptosporidium can derive nutrition while minimizing immunologic recognition and there is currently no effective treatment for cryptosporidiosis. In presented study, the life cycle of Cryptosporidium muris parasitizing gastric glands of experimentally infected laboratory rodents, Mastomys natalensis and BALB/c mice, has been analysed in detail. The main aim was to map the development of C. muris in hosts exhibiting different response to the parasitization.
Název v anglickém jazyce
Life cycle of Cryptosporidium muris in experimental conditions
Popis výsledku anglicky
Cryptosporidia (Apicomplexa) have been recently recognized as one of the most ubiquitous parasites infecting gastrointestinal and respiratory tract of vertebrates. Localization of cryptosporidian developmental stages in the host epithelium has been the subject of extensive speculation for many years. Our published data support the term epicellular to reflect the cryptosporidian localization, rather than the term intracellular extracytoplasmic, used throughout the literature. Due to its peculiar localization, Cryptosporidium can derive nutrition while minimizing immunologic recognition and there is currently no effective treatment for cryptosporidiosis. In presented study, the life cycle of Cryptosporidium muris parasitizing gastric glands of experimentally infected laboratory rodents, Mastomys natalensis and BALB/c mice, has been analysed in detail. The main aim was to map the development of C. muris in hosts exhibiting different response to the parasitization.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
EG - Zoologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GPP506%2F10%2FP372" target="_blank" >GPP506/10/P372: Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů