A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00071493" target="_blank" >RIV/00216224:14310/13:00071493 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.yrtph.2013.10.003" target="_blank" >http://dx.doi.org/10.1016/j.yrtph.2013.10.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.yrtph.2013.10.003" target="_blank" >10.1016/j.yrtph.2013.10.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

Popis výsledku v původním jazyce

Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approacheshave only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discus

Název v anglickém jazyce

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

Popis výsledku anglicky

Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approacheshave only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discus

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

<a href="/cs/project/ED0001%2F01%2F01" target="_blank" >ED0001/01/01: CETOCOEN</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

REGULATORY TOXICOLOGY AND PHARMACOLOGY

ISSN

0273-2300

e-ISSN

—

Svazek periodika

67

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

25

Strana od-do

506-530

Kód UT WoS článku

000327415300020

EID výsledku v databázi Scopus

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