Motility of Siedleckia nematoides (Apicomplexa): Structural changes of cytoskeletal structures after drugs application

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00073865" target="_blank" >RIV/00216224:14310/14:00073865 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Motility of Siedleckia nematoides (Apicomplexa): Structural changes of cytoskeletal structures after drugs application

Popis výsledku v původním jazyce

Apicomplexans belong to the most monitored group of Protista, comprising exclusively parasites of vertebrates and invertebrates. Phylum Apicomplexa is characterised by typical apical complex and a complicated cell cortex consisting of inner membrane complex (IMC) underlying the plasma membrane. The IMC is connected with numerous cytoskeletal elements such as actomyosin complex, microtubules and a network of intermediate filaments. Numerous studies report that the motile apicomplexan invasive stages, theso-called zoites, use a unique mechanism of substrate dependent gliding motility facilitated by a conserved form of actomyosin motor (the so called ?glideosome? concept). This concept was first time described in Toxoplasma gondii. The gliding motility relies on dynamic turnover of actin. Similarly apicomplexan myosins are considered unconventional and form a new class (XIV).

Název v anglickém jazyce

Motility of Siedleckia nematoides (Apicomplexa): Structural changes of cytoskeletal structures after drugs application

Popis výsledku anglicky

Apicomplexans belong to the most monitored group of Protista, comprising exclusively parasites of vertebrates and invertebrates. Phylum Apicomplexa is characterised by typical apical complex and a complicated cell cortex consisting of inner membrane complex (IMC) underlying the plasma membrane. The IMC is connected with numerous cytoskeletal elements such as actomyosin complex, microtubules and a network of intermediate filaments. Numerous studies report that the motile apicomplexan invasive stages, theso-called zoites, use a unique mechanism of substrate dependent gliding motility facilitated by a conserved form of actomyosin motor (the so called ?glideosome? concept). This concept was first time described in Toxoplasma gondii. The gliding motility relies on dynamic turnover of actin. Similarly apicomplexan myosins are considered unconventional and form a new class (XIV).

Druh

O - Ostatní výsledky

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/GBP505%2F12%2FG112" target="_blank" >GBP505/12/G112: ECIP - Evropské centrum ichtyoparazitologie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů