Mybs in mouse hair follicle development

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00076373" target="_blank" >RIV/00216224:14310/14:00076373 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/14:00436623 RIV/62157124:16170/14:43872983

Výsledek na webu

<a href="http://www.sciencedirect.com/science/journal/00408166" target="_blank" >http://www.sciencedirect.com/science/journal/00408166</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tice.2014.06.006" target="_blank" >10.1016/j.tice.2014.06.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mybs in mouse hair follicle development

Popis výsledku v původním jazyce

The Myb transcription factors are involved in essential cellular processes, such as cell proliferation, dif-ferentiation and cell death. Biological functions carried out by specific Myb proteins are distinct. Hairfollicles are ectodermal-derived organs with cycling character of the growth resulting from the pres-ence of somatic stem cells. In this study, we followed the expression of the Myb proteins in developinghair follicles and in the hair follicle stem cell niche by immunofluorescence staining. During hair follicledevelopment, B-Myb was present in a few cells located in the area of cell division; c-Myb was abun-dant postanally in dividing cells but also in keratinizing zone. In addition, c-Myb was also detected incells under the hair follicle bulge. These findings indicate possible involvement of c-Myb in regulation of activated stem cells leaving the niche.

Název v anglickém jazyce

Mybs in mouse hair follicle development

Popis výsledku anglicky

The Myb transcription factors are involved in essential cellular processes, such as cell proliferation, dif-ferentiation and cell death. Biological functions carried out by specific Myb proteins are distinct. Hairfollicles are ectodermal-derived organs with cycling character of the growth resulting from the pres-ence of somatic stem cells. In this study, we followed the expression of the Myb proteins in developinghair follicles and in the hair follicle stem cell niche by immunofluorescence staining. During hair follicledevelopment, B-Myb was present in a few cells located in the area of cell division; c-Myb was abun-dant postanally in dividing cells but also in keratinizing zone. In addition, c-Myb was also detected incells under the hair follicle bulge. These findings indicate possible involvement of c-Myb in regulation of activated stem cells leaving the niche.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Tissue and Cell

ISSN

0040-8166

e-ISSN

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Svazek periodika

46

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

352-355

Kód UT WoS článku

000343808600009

EID výsledku v databázi Scopus

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