Conformational dimorphism of isochroman-1-ones in the solid state

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00078569" target="_blank" >RIV/00216224:14310/14:00078569 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/14:43871827 RIV/70883521:28110/14:43871827

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.molstruc.2014.03.005" target="_blank" >http://dx.doi.org/10.1016/j.molstruc.2014.03.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.molstruc.2014.03.005" target="_blank" >10.1016/j.molstruc.2014.03.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Conformational dimorphism of isochroman-1-ones in the solid state

Popis výsledku v původním jazyce

Isochroman-1-one derivatives, which are relatives of coumarins, display a broad spectrum of biological activity; therefore, these derivatives attract the attention of chemists. A series of new isochroman-1-ones were prepared by the reaction of benzyl-derived Grignard reagents with acyl chlorides. All of the prepared compounds were characterized using single-crystal X-ray diffraction as well as FT-IR, NMR and MS techniques. Single crystal X-ray diffraction analysis revealed that the isochromanones can adopt two distinct conformations in the solid state. For one of the compounds, two polymorphs with unique forms crystallized separately under different temperatures. The packing of all of the examined crystals is stabilized via weak intramolecular C-H center dot center dot center dot pi and/or C-H center dot center dot center dot O interactions.

Název v anglickém jazyce

Conformational dimorphism of isochroman-1-ones in the solid state

Popis výsledku anglicky

Isochroman-1-one derivatives, which are relatives of coumarins, display a broad spectrum of biological activity; therefore, these derivatives attract the attention of chemists. A series of new isochroman-1-ones were prepared by the reaction of benzyl-derived Grignard reagents with acyl chlorides. All of the prepared compounds were characterized using single-crystal X-ray diffraction as well as FT-IR, NMR and MS techniques. Single crystal X-ray diffraction analysis revealed that the isochromanones can adopt two distinct conformations in the solid state. For one of the compounds, two polymorphs with unique forms crystallized separately under different temperatures. The packing of all of the examined crystals is stabilized via weak intramolecular C-H center dot center dot center dot pi and/or C-H center dot center dot center dot O interactions.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Molecular Structure

ISSN

0022-2860

e-ISSN

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Svazek periodika

1078

Číslo periodika v rámci svazku

december

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

106-113

Kód UT WoS článku

000343845100012

EID výsledku v databázi Scopus

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