The possible relationship between PAX9 gene polymorphisms and tooth agenesis in the Czech population

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00080151" target="_blank" >RIV/00216224:14310/14:00080151 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The possible relationship between PAX9 gene polymorphisms and tooth agenesis in the Czech population

Popis výsledku v původním jazyce

Tooth agenesis is the most prevalent craniofacial congenital malformation in humans. Under the term tooth agenesis we understand absence of one or more teeth in the dentition. Up to 25 % of the population may lose at least one third molar. Agenesis of other permanent teeth, excluding third molars, ranges from 1,6 to 9,6 %, depending on the population studied. Primary dentition may also be affected, but with lower prevalence (from 0,5 to 0,9 %). This disorder can have a variety of causes ? from the influence of local causes during the formation of tooth germs primarily to the influence of genetic factors. Odontogenesis is very complicated and complex process involving over 300 so far identified that mediate interplay between cells of dental epithelium and adjacent mesenchyme. These molecules interact each other and create a complex system of regulatory linkages which monitors and controls the entire process of odontogenesis.

Název v anglickém jazyce

The possible relationship between PAX9 gene polymorphisms and tooth agenesis in the Czech population

Popis výsledku anglicky

Tooth agenesis is the most prevalent craniofacial congenital malformation in humans. Under the term tooth agenesis we understand absence of one or more teeth in the dentition. Up to 25 % of the population may lose at least one third molar. Agenesis of other permanent teeth, excluding third molars, ranges from 1,6 to 9,6 %, depending on the population studied. Primary dentition may also be affected, but with lower prevalence (from 0,5 to 0,9 %). This disorder can have a variety of causes ? from the influence of local causes during the formation of tooth germs primarily to the influence of genetic factors. Odontogenesis is very complicated and complex process involving over 300 so far identified that mediate interplay between cells of dental epithelium and adjacent mesenchyme. These molecules interact each other and create a complex system of regulatory linkages which monitors and controls the entire process of odontogenesis.

Druh

O - Ostatní výsledky

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT11420" target="_blank" >NT11420: Molekulární diagnostika hypodoncie a možnosti zubních autotransplantací</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů