Inhibitory serinových peptidáz (SERPINY) parazitického organismu Eudiplozoon nipponicum (Monogenea)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00087987" target="_blank" >RIV/00216224:14310/16:00087987 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Inhibitory serinových peptidáz (SERPINY) parazitického organismu Eudiplozoon nipponicum (Monogenea)

Popis výsledku v původním jazyce

Our experimental organisms Eudiplozoon nipponicum (family Diplozoidae, Polyopisthocotylea) is hematophagous ectoparasite from the gills of cyprinid fish (Cyprinus carpio). The properties of proteins (e.g. function) of the members from the family Monogenea are among the less investigated in whole phylum Platyhelminthes. During the previous experimental work, interesting results concerning the bioactive molecules of E. nipponicum (endopeptidases and their inhibitors) were recorded. Some of these molecules are probably presented in excretory-secretory products (secretome) of the parasite and thus potentially involved in parasite-host interactions. Therefore, we performed the complete mass spectrometry analysis of E. nipponicum secretome (LC MS/MS). Some of the identified protein molecules, such as e.g. serpins, were selected and further characterized.

Název v anglickém jazyce

Inhibitory serinových peptidáz (SERPINY) parazitického organismu Eudiplozoon nipponicum (Monogenea)

Popis výsledku anglicky

Our experimental organisms Eudiplozoon nipponicum (family Diplozoidae, Polyopisthocotylea) is hematophagous ectoparasite from the gills of cyprinid fish (Cyprinus carpio). The properties of proteins (e.g. function) of the members from the family Monogenea are among the less investigated in whole phylum Platyhelminthes. During the previous experimental work, interesting results concerning the bioactive molecules of E. nipponicum (endopeptidases and their inhibitors) were recorded. Some of these molecules are probably presented in excretory-secretory products (secretome) of the parasite and thus potentially involved in parasite-host interactions. Therefore, we performed the complete mass spectrometry analysis of E. nipponicum secretome (LC MS/MS). Some of the identified protein molecules, such as e.g. serpins, were selected and further characterized.

Druh

O - Ostatní výsledky

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/GBP505%2F12%2FG112" target="_blank" >GBP505/12/G112: ECIP - Evropské centrum ichtyoparazitologie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů