Characterization of total retinoid-like activity of compounds produced by three common phytoplankton species

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088800" target="_blank" >RIV/00216224:14310/16:00088800 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S156898831630021X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S156898831630021X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.hal.2016.11.002" target="_blank" >10.1016/j.hal.2016.11.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Characterization of total retinoid-like activity of compounds produced by three common phytoplankton species

Popis výsledku v původním jazyce

Phytoplankton can produce various bioactive metabolites, which may affect other organisms in the aquatic environment. This study provides the first information on the total retinoid-like activity associated with both intracellular and extracellular metabolites produced by selected phytoplankton species that could play a role in teratogenic effects and developmental disruption in exposed organisms. The studied species included a coccoid cyanobacteria, a filamentous cyanobacteria and a green alga, all of which commonly occur in freshwater bodies in Europe. Methanolic extracts from cellular material and extracellular exudates were prepared from cultures cultivated in two light-intensity variants with five replicates for each species. The retinoid-like activity was evaluated by in vitro assays along with chemical analyses of two potent retinoic acids (all-trans retinoic acid (ATRA) and 9cis-RA).

Název v anglickém jazyce

Characterization of total retinoid-like activity of compounds produced by three common phytoplankton species

Popis výsledku anglicky

Phytoplankton can produce various bioactive metabolites, which may affect other organisms in the aquatic environment. This study provides the first information on the total retinoid-like activity associated with both intracellular and extracellular metabolites produced by selected phytoplankton species that could play a role in teratogenic effects and developmental disruption in exposed organisms. The studied species included a coccoid cyanobacteria, a filamentous cyanobacteria and a green alga, all of which commonly occur in freshwater bodies in Europe. Methanolic extracts from cellular material and extracellular exudates were prepared from cultures cultivated in two light-intensity variants with five replicates for each species. The retinoid-like activity was evaluated by in vitro assays along with chemical analyses of two potent retinoic acids (all-trans retinoic acid (ATRA) and 9cis-RA).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DA - Hydrologie a limnologie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Harmful Algae

ISSN

1568-9883

e-ISSN

—

Svazek periodika

60

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

157-166

Kód UT WoS článku

000390516200015

EID výsledku v databázi Scopus

—