Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F18%3A00104735" target="_blank" >RIV/00216224:14310/18:00104735 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.rsc.org/en/Content/ArticleLanding/2018/PP/C8PP00096D#!divAbstract" target="_blank" >https://pubs.rsc.org/en/Content/ArticleLanding/2018/PP/C8PP00096D#!divAbstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c8pp00096d" target="_blank" >10.1039/c8pp00096d</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

Popis výsledku v původním jazyce

To date, most known molecules that release carbon monoxide by the action of light are based on carbonyl complexes of metals. However, they suffer from several disadvantages, so the focus of this perspective is on photoactivatable metal-free CO precursors. The development and design of these systems from the starting point of deep-UV-absorbing hydrophobic molecules and leading to hydrophilic biocompatible visible-light-absorbing CO-releasing molecules (photoCORMs) is described with mechanistic details for several structural motifs. The possibilities of this development are not exhausted and here we discuss the design of new biologically interesting candidates.

Název v anglickém jazyce

Visible-light-activated photoCORMs: rational design of CO-releasing organic molecules absorbing in the tissue-transparent window

Popis výsledku anglicky

To date, most known molecules that release carbon monoxide by the action of light are based on carbonyl complexes of metals. However, they suffer from several disadvantages, so the focus of this perspective is on photoactivatable metal-free CO precursors. The development and design of these systems from the starting point of deep-UV-absorbing hydrophobic molecules and leading to hydrophilic biocompatible visible-light-absorbing CO-releasing molecules (photoCORMs) is described with mechanistic details for several structural motifs. The possibilities of this development are not exhausted and here we discuss the design of new biologically interesting candidates.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

<a href="/cs/project/LM2015051" target="_blank" >LM2015051: Centrum pro výzkum toxických látek v prostředí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PHOTOCHEMICAL &amp; PHOTOBIOLOGICAL SCIENCES

ISSN

1474-905X

e-ISSN

—

Svazek periodika

17

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

19

Strana od-do

692-710

Kód UT WoS článku

000435358900001

EID výsledku v databázi Scopus

2-s2.0-85048624438