THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F18%3A00113181" target="_blank" >RIV/00216224:14310/18:00113181 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26210/18:PU139953

Výsledek na webu

<a href="https://www.engmech.cz/im/proceedings/show_p/2018/725" target="_blank" >https://www.engmech.cz/im/proceedings/show_p/2018/725</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21495/91-8-725" target="_blank" >10.21495/91-8-725</a>

Jazyk výsledku

angličtina

Název v původním jazyce

THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT

Popis výsledku v původním jazyce

The main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, gamma-globulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement.

Název v anglickém jazyce

THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT

Popis výsledku anglicky

The main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, gamma-globulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

ENGINEERING MECHANICS 2018 PROCEEDINGS, VOL 24

ISBN

9788086246888

ISSN

1805-8248

e-ISSN

1805-8256

Počet stran výsledku

4

Strana od-do

725-728

Název nakladatele

ACAD SCI CZECH REPUBLIC, INST THEORETICAL &amp; APPLIED MECHANICS

Místo vydání

PRAGUE 9

Místo konání akce

Svratka, CZECH REPUBLIC

Datum konání akce

14. 5. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000465489800181