Benefits of functional PCA in the analysis of single-trial auditory evoked potentials

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F19%3A00107161" target="_blank" >RIV/00216224:14310/19:00107161 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00180-018-0819-6" target="_blank" >https://link.springer.com/article/10.1007%2Fs00180-018-0819-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00180-018-0819-6" target="_blank" >10.1007/s00180-018-0819-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Benefits of functional PCA in the analysis of single-trial auditory evoked potentials

Popis výsledku v původním jazyce

Evoked potentials reflect neural processing and are widely used to studying sensory perception. Here we applied a functional approach to studying single-trial auditory evoked potentials in the rat model of tinnitus, in which overdoses of salicylate are known to alter sound perception characteristically. Single-trial evoked potential integrals were generated with sound stimuli (tones and clicks) presented systematically over an intensity range and further assessed using the functional principal component analysis. Comparisons between the single-trial responses for each sound type and each treatment were done by inspecting the scores corresponding to the first two principal components. An analogous analysis was performed on the first derivative of the response functions. We conclude that the functional principal component analysis is capable of differentiating between the controls and salicylate treatments for each type of sound. It also well separates the response function for tones and clicks. The results of linear discriminant analysis show, that scores of the first two principal components are effective cluster predictors. However, the distinction is less pronounced in case the first derivative of the response.

Název v anglickém jazyce

Benefits of functional PCA in the analysis of single-trial auditory evoked potentials

Popis výsledku anglicky

Evoked potentials reflect neural processing and are widely used to studying sensory perception. Here we applied a functional approach to studying single-trial auditory evoked potentials in the rat model of tinnitus, in which overdoses of salicylate are known to alter sound perception characteristically. Single-trial evoked potential integrals were generated with sound stimuli (tones and clicks) presented systematically over an intensity range and further assessed using the functional principal component analysis. Comparisons between the single-trial responses for each sound type and each treatment were done by inspecting the scores corresponding to the first two principal components. An analogous analysis was performed on the first derivative of the response functions. We conclude that the functional principal component analysis is capable of differentiating between the controls and salicylate treatments for each type of sound. It also well separates the response function for tones and clicks. The results of linear discriminant analysis show, that scores of the first two principal components are effective cluster predictors. However, the distinction is less pronounced in case the first derivative of the response.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10103 - Statistics and probability

Projekt

<a href="/cs/project/GA15-06991S" target="_blank" >GA15-06991S: Analýza funkcionálních dat a související témata</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Computational Statistics

ISSN

0943-4062

e-ISSN

1613-9658

Svazek periodika

34

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

13

Strana od-do

617-629

Kód UT WoS článku

000467230100010

EID výsledku v databázi Scopus

2-s2.0-85064808707